Obesity as a comorbid factor in a boy with psoriasis vulgaris

Yunanto, Kun Anggi; Waspodo, Nurelly; Tabri, Farida; Ilyas, Faridha

doi:10.1016/j.enfcli.2019.10.018

Cited by 2 publications

(3 citation statements)

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“…Moreover, if both parents have psoriasis, the risk increases by 50 per cent [ 44 , 116 ]. The genetic factor governing psoriasis is explained by the disease’s presence in offspring and described in siblings [ 117 ]. In one-third of psoriatic patients, first- and second-degree relatives have a higher incidence of developing Psoriasis Vulgaris; in turn, for a child born from parents with psoriasis, the risk is 50%, while this risk decreases to 8% if only one sibling has psoriasis [ 118 ].…”

Section: The Link Between Psoriasis and Obesitymentioning

confidence: 99%

“…The more common clinical picture of psoriasis is a well-circumscribed erythematous plaque covered with white or silvery scales, which can be large or small [ 40 ], thick or thin [ 118 ]. These lesions affect extensor surfaces such as elbows, knees, and the navel, lumbosacral region and scalp [ 117 ], representing three-quarters of all psoriatic patients [ 39 ], commonly known as chronic plaque psoriasis [ 31 , 32 , 47 ] or Psoriasis Vulgaris. Other but less frequent types of psoriasis are inverse Psoriasis, palmoplantar Psoriasis, erythrodermic Psoriasis, guttate Psoriasis and pustular psoriasis [ 39 ].…”

Section: The Link Between Psoriasis and Obesitymentioning

confidence: 99%

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Exploring the Links between Obesity and Psoriasis: A Comprehensive Review

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et al. 2022

IJMS

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Obesity is a major public health issue worldwide since it is associated with the development of chronic comorbidities such as type 2 diabetes, dyslipidemias, atherosclerosis, some cancer forms and skin diseases, including psoriasis. Scientific evidence has indicated that the possible link between obesity and psoriasis may be multifactorial, highlighting dietary habits, lifestyle, certain genetic factors and the microbiome as leading factors in the progress of both pathologies because they are associated with a chronic pro-inflammatory state. Thus, inflammation management in obesity is a plausible target for psoriasis, not only because of the sick adipose tissue secretome profile but also due to the relationship of obesity with the rest of the immune derangements associated with psoriasis initiation and maintenance. Hence, this review will provide a general and molecular overview of the relationship between both pathologies and present recent therapeutic advances in treating this problem.

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Section: The Link Between Psoriasis and Obesitymentioning

confidence: 99%

Section: The Link Between Psoriasis and Obesitymentioning

confidence: 99%

Exploring the Links between Obesity and Psoriasis: A Comprehensive Review

Barros

Durán

Vera

et al. 2022

IJMS

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“…Relevant scholars observed the changes in clinical PASI score and vascular dilatation under dermatoscope after treatment, and the relative index was used to calculate the evaluation index [ 36 ]. Many published evaluation indicators for observing curative effect are compared with the decline rate.…”

Section: Resultsmentioning

confidence: 99%

Data Mining and Meta-Analysis of Psoriasis Based on Association Rules

Zhang

2022

Journal of Healthcare Engineering

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Psoriasis is a common chronic and recurrent disease in dermatology, which has a great impact on the physical and mental health of patients. Meta-analysis can evaluate the effectiveness and safety of defubao in the treatment of psoriasis vulgaris. This article observes psoriasis skin lesions treated with topical defubao and the changes in blood vessels under dermoscopy. Considering that the Apriori algorithm and the existing improved algorithm have the problems of ignoring the weight and repeatedly scanning the database, this paper proposes a matrix association rule method based on random forest weighting. This method uses the random forest algorithm to assign weights to each item in the data set, and introduces matrix theory to convert the transaction data set into a matrix form and store it, thereby improving operating efficiency. This article included 11 studies, of which 7 studies used the indicator “Researcher’s Overall Assessment” (IGA) to evaluate the efficacy, 5 studies used the “Patient Overall Assessment” (PGA) as the efficacy evaluation index, and Loss Area and Severity Index (PASI) was used as an observation index to evaluate the efficacy. Seven studies conducted safety comparisons. In this paper, IGA and PGA were used as evaluation indicators. The treatment effect of the defubao group was better than the calcipotriol group and the betamethasone group. The differences were statistically significant. The effect of the Fubao treatment for 8 weeks is significantly better than that of 4 weeks and 2 weeks, and the differences are statistically different. Using PASI as the evaluation index, a descriptive study was carried out, and it was found that after 4 weeks of treatment for psoriasis vulgaris, the average PASI reduction rate of patients was higher than that of the calcipotriol group and the betamethasone group. The safety evaluation found that after 8 weeks of treatment, the incidence of adverse events in the defubao group was significantly lower than that in the calcipotriol group.

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Obesity as a comorbid factor in a boy with psoriasis vulgaris

Cited by 2 publications

References 10 publications

Exploring the Links between Obesity and Psoriasis: A Comprehensive Review

Exploring the Links between Obesity and Psoriasis: A Comprehensive Review

Data Mining and Meta-Analysis of Psoriasis Based on Association Rules

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