Obesity, depression and hip pain

Schwarze, Martin; Haüser, Winfried; Schmutzer, Gabriele; Brähler, Elmar; Beckmann, Nicholas A.; Schiltenwolf, Marcus

doi:10.1002/msc.1380

Cited by 24 publications

(26 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“… 27 Moreover, a cross-sectional study of 2515 adult participants has suggested that elevated depression scores were significantly and independently associated with disabling chronic hip pain. 29 Although genetic factors are likely to contribute to pain at different sites, our negative findings suggest that nongenetic triggers may be more relevant in the co-occurrence of facial, knee, or hip pain with depression. However, although our results suggest a strong evidence of null association of depression with facial, hip, and knee pain (ORs virtually equal to 1), we had limited power for these 3 pain traits due to small sample sizes.…”

Section: Discussionmentioning

confidence: 71%

Reciprocal interaction between depression and pain: results from a comprehensive bidirectional Mendelian randomization study and functional annotation analysis

Tang

Wang

Hägg

et al. 2021

Pain

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 71%

Reciprocal interaction between depression and pain: results from a comprehensive bidirectional Mendelian randomization study and functional annotation analysis

Tang

Wang

Hägg

et al. 2021

Pain

View full text Add to dashboard Cite

show abstract

“…A total of 6,049 studies were excluded based on the screening of titles and abstracts, leaving 193 studies for full text analysis. A further 74 studies were excluded as they did not meet the review’s inclusion criteria: 37 studies only included BMI as their measure of obesity [ 17 – 51 ], 18 studies did not examine any associations between fat mass and pain [ 50 , 52 – 67 ], nine studies examined adiposity within a specific muscle [ 68 – 75 ], five studies did not specify a site of pain [ 76 – 79 ], two studies only examined multisite pain [ 80 , 81 ], and three studies examined pain in children [ 82 – 84 ].…”

Section: Resultsmentioning

confidence: 99%

Is adiposity associated with back and lower limb pain? A systematic review

et al. 2021

View full text Add to dashboard Cite

Background Back and lower limb pain have a major impact on physical function and quality of life. While obesity is a modifiable risk factor for musculoskeletal pain, the role of adiposity is less clear. This systematic review aimed to examine the relationship between both adiposity and its distribution and back and lower limb pain. Methods A systematic search of electronic databases was conducted to identify studies that examined the association between anthropometric and/or direct measures of adiposity and site specific musculoskeletal pain. Risk of bias was assessed and a best evidence synthesis was performed. Results A total of 56 studies were identified which examined 4 pain regions, including the lower back (36 studies), hip (two studies), knee (13 studies) and foot (eight studies). 31(55%) studies were assessed as having low to moderate risk of bias. 17(30%) studies were cohort in design. The best evidence synthesis provided evidence of a relationship between central adiposity and low back and knee pain, but not hip or foot pain. There was also evidence of a longitudinal relationship between adiposity and the presence of back, knee and foot pain, as well as incident and increasing foot pain. Conclusions This systematic review provides evidence of an association between both body fat and its central distribution and low back and knee pain, and a longitudinal relationship between adiposity and back, knee and foot pain. These results highlight the potential for targeting adiposity in the development of novel treatments at these sites.

show abstract

“…On the other hand, since possible causes of hip osteoarthritis pain may be largely behavioral, a carefully organized set of behavioral based interventions, may predictably assist in efforts to reduce, reverse, or minimize the extent of hip osteoarthritis pain and suffering in many cases without excessive reliance on surgery, as proposed by Ren et al [52], as well as in those undergoing surgery [87]. In particular, to avert the likelihood of any ensuing peripheral and central sensitization and neuropathic pain syndromes as is being observed in this progressive disease quite frequently in recent research studies, the clinician or primary caregiver should spare no efforts in collaborating with the patient to apprise them of injurious behaviors that can exacerbate their pain.…”

Section: Discussionmentioning

confidence: 99%

Hip Joint Osteoarthritis Pain Sources and Control

Marks¹

2020

PST

View full text Add to dashboard Cite

Hip joint osteoarthritis, a widespread disabling disease with no known cause, produces considerable bouts of intractable pain as a result of multiple disease associated problems. This paper examines some sources of osteoarthritic hip joint pain, a poorly understood topic at best. Presented in three parts are data retrieved from several sources, including animal models. It is concluded that to improve the effectiveness of treatments designed to minimize hip osteoarthritis pain, a better understanding of the diverse origins of hip joint pain, and hip joint neurology, may permit the development of more precise as well as targeted pain strategies.

show abstract

Obesity, depression and hip pain

Abstract: Introduction: Up to 64% of the general population reports experiencing chronic pain,

Cited by 24 publications

References 33 publications

Reciprocal interaction between depression and pain: results from a comprehensive bidirectional Mendelian randomization study and functional annotation analysis

Reciprocal interaction between depression and pain: results from a comprehensive bidirectional Mendelian randomization study and functional annotation analysis

Is adiposity associated with back and lower limb pain? A systematic review

Hip Joint Osteoarthritis Pain Sources and Control

Contact Info

Product

Resources

About