Obesity, Exercise and Orthopedic Disease

Frye, Christopher W.; Shmalberg, Justin; Wakshlag, Joseph J.

doi:10.1016/j.cvsm.2016.04.006

Cited by 45 publications

(46 citation statements)

References 73 publications

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“…DM was not associated with OA in either gender in this study. Overweight status has been shown to be strongly associated with OA, and physical activity tends to lower BMI [29,30]. Therefore, the fact that the green and blue collar occupations involved higher levels of physical activity may have influenced the results of this study.…”

Section: Discussionmentioning

confidence: 97%

The Association between Osteoarthritis and Occupational Clusters in the Korean Population: A Nationwide Study

et al. 2017

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Osteoarthritis (OA) is a considerable health problem worldwide. It is known to be associated with certain occupational risk factors. We examined the prevalence rate of OA by occupational cluster. Data were collected from the Korea National Health and Nutrition Examination Surveys (2010–2013). The total number of unweighted sample size was 9,905 participants: 4,460 men and 5,445 women, and OA prevalence was 5.3% and 18.4% respectively. OA patients were defined as participants with knee/hip joint pain and radiographic change of knee/hip joint. Occupational type was classified as either white, pink, blue, or green collar based on the occupational characteristics following physical demand: white for manager and professionals; pink for clerks and service/sales workers; blue for craft/trade workers, machine operators and assemblers, and elementary manual workers; and green for agricultural/fishery workers. We calculated the odds ratios (ORs) and 95% confidence intervals (95% CI) for the odds of a participant’s having OA according to the occupational cluster, with gender stratification. The multiple logistic regression model showed that, compared to the white collar group, the ORs of the pink, blue, and green collar workers were 1.23 (95% CI 0.64–2.36), 1.85 (95% CI 1.18–2.88), and 2.91 (95% CI 1.86–4.54), respectively, in males, and 2.53 (95% CI 1.71–3.73), 2.86 (95% CI 1.94–4.21), and 3.90 (95% CI 2.60–5.83), respectively in females. The prevalence rate of OA was associated with the occupational cluster, in order from highest to lowest: green, blue, pink, and white collar.

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Section: Discussionmentioning

confidence: 97%

The Association between Osteoarthritis and Occupational Clusters in the Korean Population: A Nationwide Study

et al. 2017

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“…Common non-surgical treatments include non-steroidal anti-inflammatory drugs (NSAIDs), weight management, joint supplements, and physiotherapy. [4][5][6] Because NSAIDs may have potentially serious adverse effects, are contraindicated in many patients with a history of intolerance or certain comorbidities, and might not provide sufficient pain control, other analgesic options deserve exploration. [7][8][9] Orthobiologic products (such as mesenchymal stem cells, bone marrow aspirate concentrate, and platelets rich products) are showing promise as safe and effective treatments for musculoskeletal diseases including osteoarthritis in people and animals.…”

Section: Introductionmentioning

confidence: 99%

<p>Assessment of a Single Intra-Articular Stifle Injection of Pure Platelet Rich Plasma on Symmetry Indices in Dogs with Unilateral or Bilateral Stifle Osteoarthritis from Long-Term Medically Managed Cranial Cruciate Ligament Disease</p>

Venator¹,

Frye²,

Gamble³

et al. 2020

VMRR

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These authors contributed equally to this workPurpose: The use of platelet-rich plasma (PRP) to treat canine osteoarthritis has gained support within the scientific community. PRP effects on pain control for degenerative joint disease induced by naturally occurring cranial cruciate ligament instability are limited, particularly in a cohort of dogs with chronic instability and osteoarthritis (>12 months), representing a commonly encountered clinical population that often defaults to medical management. The goal of this study was to assess the effects of a single intra-articular PRP injection into an effected stifle in this cohort, to assess response to treatment, quantitative kinetic data as it relates to percent body weight for peak vertical force (PVF) and vertical impulse (VI) were collected, and symmetry indices related to PVF were determined. Methods: Twelve dogs with unilateral or bilateral osteoarthritis with ruptured, nonstabilized cranial cruciate ligaments over 12 months duration were identified. Unilateral injections of 2.5 mL of a PRP preparation into the most severely affected stifle based on kinetic analysis was performed. Repeat pressure-sensitive walkway analysis was conducted monthly for 3 months. Peak vertical force (PVF) and vertical impulse (VI) were normalized to body weight and identified in all four limbs. Previously published symmetry indices regarding PVF were calculated, comparing the treated limb with the contralateral limb, ipsilateral forelimb, and contralateral forelimb. Results: After treatment, hind limb symmetry index (SI) regarding PVF showed improved symmetry, suggesting more weight placement at all-time points after injection of the most affected limb (p < 0.01). Further, PVF asymmetry indices assessing contralateral fore (CFL) and hind limb (CHL) as well as ipsilateral forelimb (IFL) revealing a significant decrease from baseline for CHL at week 4 (p = 0.02), but not weeks 8 and 12. The CFL showed decreased differences in symmetry from baseline at each time point (p = 0.03). There were no statistically significant changes in PVF or VI over time in treated dogs. Conclusion: A single injection of PRP improved kinetics for minimally 4 weeks with some data suggesting an effect for up to 12 weeks. Therefore, PRP might be a viable therapeutic option for instability and inflammation associated with chronic osteoarthritis due to cranial cruciate ligament disease in the non-surgical patient.

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“…Ressalta-se ainda a adaptação do ambiente a condição de animais com osteoartrite e a adequação de determinados hábitos, incluindo escovações diárias, colocação de suportes de elevação nos comedouros e bebedouros, aquisição de vasilhas de eliminação mais rasas, utilização de degraus e/ou rampas de acesso aos locais elevados nos quais o animal costuma pular para acessar, emprego de materiais acolchoados sobre os locais de repouso, arranhadores horizontais, bem como prevenção e tratamento da obesidade e controle de exercícios moderados (Hardie, 1997;Bennett et al, 2012;Davies, 2016;Frye et al, 2016).…”

Section: Discussionunclassified

Osteocondrodisplasia em um felino jovem da raça Scottish Fold: relato de caso

Jardim¹,

Farias²,

Cid³

et al. 2017

BJVM

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RELATO DE CASOCopyright Jardim et al. Este é um artigo publicado em acesso aberto (Open Access) sob a licença Creative Commons Attribution Non-Commercial, que permite uso, distribuição e reprodução em qualquer meio, sem restrições desde que sem fins comerciais e que o trabalho original seja corretamente citado.Osteocondrodisplasia em um felino jovem da raça Scottish Fold: relato de caso ResumoOs gatos Scottish Fold possuem um gene autossômico dominante que determina a ocorrência das orelhas dobradas para frente e graus variados de osteocondrodisplasia. Objetiva-se com este trabalho relatar um caso de osteocondrodisplasia em um gato jovem da raça Scottish Fold, destacando as características clínicas, patológicas e a conduta terapêutica adotada mediante o quadro clínico, visando difundir informações relacionadas ás particularidades deste padrão racial felino. Foi levado para atendimento clínico um gato doméstico da raça Scottish Fold, macho, com 12 meses de idade, devido à queixa de dificuldade locomotora. Na avaliação radiográfica as articulações társicas apresentaram-se hipoplásicas, com angulação anormal do eixo nos metatarsos, falanges e articulações relacionadas, compatível com osteocondrodisplasia. Já nas articulações coxofemorais evidenciou-se displasia coxofemoral leve. O tratamento consistiu na utilização de gabapentina, sulfato de condroitina e ômega-3. Este é o primeiro relato de osteocondrodisplasia em um Scottish Fold no Brasil. As deformidades osteoarticulares observadas no felino jovem da raça Scottish Fold com osteocondrodisplasia constituem uma preocupação, em função do comprometimento da qualidade de vida do paciente e ausência de um tratamento curativo para tal afecção, assim o estudo pôde expandir informações a respeito das características inerentes a este padrão racial.Palavras-chave: gatos, mutações genéticas, doenças osteoarticulares. AbstractScottish Fold cats have an autosomal dominant gene that determines the occurrence of forward-bent ears and varying degrees of osteochondrodysplasia. The objective of this work is to report a case of osteochondrodysplasia in a young Scottish Fold cat, highlighting the clinical and pathological characteristics and the therapeutic behavior adopted by the clinical picture, aiming to disseminate information related to the particularities of this feline racial pattern. A Scottish Fold male domestic cat, 12 months old, was brought to clinical care due to the complaint of locomotor difficulty. In the radiographic evaluation, the tarsal joints were hypoplastic, with abnormal axis angulation in the metatarsals, phalanges and related joints, compatible with osteochondrodysplasia. Already in the hip joints, mild hip dysplasia was evident. Treatment consisted of gabapentin, chondroitin sulfate and omega-3. This is the first report of osteochondrodysplasia in a Scottish Fold in Brazil. The osteoarticular deformities observed in the Scottish Fold feline with osteochondrodysplasia are a concern, due to the patient's quality of life impairment and the absence of a cura...

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Obesity, Exercise and Orthopedic Disease

Cited by 45 publications

References 73 publications

The Association between Osteoarthritis and Occupational Clusters in the Korean Population: A Nationwide Study

The Association between Osteoarthritis and Occupational Clusters in the Korean Population: A Nationwide Study

<p>Assessment of a Single Intra-Articular Stifle Injection of Pure Platelet Rich Plasma on Symmetry Indices in Dogs with Unilateral or Bilateral Stifle Osteoarthritis from Long-Term Medically Managed Cranial Cruciate Ligament Disease</p>

Osteocondrodisplasia em um felino jovem da raça Scottish Fold: relato de caso

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