Obesity Management Task Force of the European Association for the Study of Obesity Released “Practical Recommendations for the Post-Bariatric Surgery Medical Management”

Busetto, Luca; Dicker, Dror; Azran, Carmil; Batterham, Rachel L.; Farpour‐Lambert, Nathalie; Fried, Martin; Hjelmesæth, Jøran; Kinzl, Johann F.; Leitner, Deborah R.; Makaronidis, Janine; Schindler, Karin; Toplak, Hermann; Yumuk, Volkan

doi:10.1007/s11695-018-3283-z

Cited by 113 publications

(106 citation statements)

References 4 publications

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“…Some studies observed that time to pregnancy after bariatric surgery, as well as pre-pregnancy weight loss, was associated with perinatal complications [21]. Therefore, several authors recommended to delay pregnancy for at least 12 to 18 month after bariatric operation as pregnancy within this catabolic time frame might lead to altered nutritional supply, and therefore triggering the development of SGA infants [22,23]. In contrast, others found no differences in neonatal birth weight and adverse pregnancy outcomes between women who conceived within the first postoperative year and those who conceived later [24].…”

Section: Discussionmentioning

confidence: 99%

Trajectories of Fetal Adipose Tissue Thickness in Pregnancies After Gastric Bypass Surgery

et al. 2019

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Purpose Recent studies showed that women after surgery are at higher risk of delivering small-for-gestational infants. Thus, this study aims to investigate longitudinal changes of fetal subcutaneous adipose tissue thickness (FSCTT) of fetuses conceived after gastric bypass surgery as compared to BMI-matched controls. Methods Retrospective cohort study measuring ultrasound-derived longitudinal trajectories of abdominal FSCTT in 41 singleton pregnancies after gastric bypass surgery compared to 41 BMI-matched controls and 64 obese mothers.Results FSCTT was significantly lower in fetuses of women after GB as compared to BMI-matched controls in the second (mean difference 1.38 mm, p < 0.001) and third trimester of gestation (mean difference 3.37 mm, p < 0.001). Longitudinal analysis revealed significant differences in mean FSCTT trajectories between offspring's in GB mothers, BMI-matched, or obese controls. The ratio of FSCTT and abdominal circumference remained constant in the BMI-matched control group whereas it significantly decreased in fetuses of women after GB. Despite remarkable differences were observed in longitudinally assessed FSCTT, further analyses in the GB subgroup revealed that FSCTT were not influenced by OGTT mean or 120 min glucose values, biochemically hypoglycemia, time since bariatric surgery, or weight loss since surgery. Conclusion In fetuses of mothers with history of bariatric surgery, abdominal FSCTT was markedly reduced. While the underlying mechanisms are not fully understood, a multifactorial genesis including nutritional deficiencies and altered metabolism after bariatric surgery is assumed.

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Section: Discussionmentioning

confidence: 99%

Trajectories of Fetal Adipose Tissue Thickness in Pregnancies After Gastric Bypass Surgery

et al. 2019

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“…Nowadays, bariatric surgery is the most efficient method of obesity treatment [12]. Many studies have shown that bariatric surgery not only helps patients achieve long-term weight loss but also removes obesity-related complications, including T2DM and high blood pressure [13][14][15][16]. It has been demonstrated that weight-loss by laparoscopic sleeve gastrectomy leads to a 40%-65% reduction in excess weight.…”

Section: Introductionmentioning

confidence: 99%

A Longitudinal Study of the Antioxidant Barrier and Oxidative Stress in Morbidly Obese Patients after Bariatric Surgery. Does the Metabolic Syndrome Affect the Redox Homeostasis of Obese People?

Choromańska

Myśliwiec

Łuba

et al. 2020

JCM

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This is the first study to evaluate both the antioxidant barrier, glutathione metabolism, and oxidative damage to proteins and lipids in morbidly obese patients undergoing bariatric treatment. The study included 65 patients with class 3 obesity divided into two subgroups: morbidly obese patients without metabolic syndrome (OB) and obese patients with metabolic syndrome (OB + MS). Blood samples were collected before surgery as well as one, three, six, and twelve months after the bariatric treatment. Superoxide dismutase and reduced glutathione (GSH) were significantly decreased, whereas glutathione reductase and uric acid were enhanced in morbidly obese patients before bariatric surgery as compared to lean control. Moreover, in the OB group, we observed the increase of superoxide dismutase (SOD) and the decrease of uric acid (UA) after the bariatric treatment; however, these changes were not observed in the OB + MS group. The oxidative damage to proteins (advanced glycation end products, AGE; advanced oxidation protein products, AOPP) and lipids (8-isoprostanes, 8-isop; 4-hydroxynoneal) was higher in OB as well as OB + MS patients. We noticed that AGE and AOPP levels diminished after the bariatric treatment, whereas redox status (ratio of GSH to oxidized glutathione) was still reduced in the OB + MS group. Summarizing, morbid obesity is associated with disturbances in the antioxidant barrier and enhanced oxidative damage to proteins and lipids. Although bariatric surgery improves redox homeostasis in obese patients, those with metabolic syndrome show a continuous decrease in the antioxidant status. In patients undergoing bariatric treatment, antioxidant supplementation may be considered.

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“…Although psychological evaluation is mandatory for most surgery programs, there are no clear guidelines about what that assessment must involve [6]. In addition, after the procedure, psychological counseling is often neglected, which may have an impact on weight variation and in the achievement of long-term goals in this group of patients [7].…”

Section: Introductionmentioning

confidence: 99%

“…As is well known, weight regain after BS can occur and therefore all efforts must be made in order to prevent such occurrence. Several factors can explain this, each of which has high interindividual variability [7,8].…”

Section: Introductionmentioning

confidence: 99%

Impact of Depression on Weight Variation after Bariatric Surgery: A Three-Year Observational Study

et al. 2020

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Introduction: The association between obesity and depression has been repeatedly established. However, little is known about the impact that the diagnosis of depression before bariatric surgery (DDBS) may have on weight loss. Objective: To evaluate the impact of DDBS on weight outcomes. Methods: Retrospective study of patients submitted to BS. Patients with no weight, no current medication data, or those submitted to revision surgery were excluded. Patients were considered to have DDBS based on taking antidepressants prior to BS or if there was a medical history of past or current depression. Patients with and without a depression history were compared using independent t test. A multivariate logistic regression model was created to evaluate predictors of weight variation (variables included: age, sex, and type of surgery). Results: A total of 616 patients did not have a history of depression and 230 had DDBS. There was a statistically significant difference in the BMI variation between groups. On average, individuals with DDBS lost 1.4 kg/m 2 less than those without DDBS. In the multivariate analysis, the group with DDBS, compared with the group without DDBS, presented on average less -0.9 kg/m 2 (95% CI -1.7 to -0.2, p = 0.018) BMI variation. Conclusion: DDBS is a predictor of lower weight loss after the surgical procedure. Even after adjusting for confounding variables such as age, sex, and BS type, this effect remains.

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Obesity Management Task Force of the European Association for the Study of Obesity Released “Practical Recommendations for the Post-Bariatric Surgery Medical Management”

Cited by 113 publications

References 4 publications

Trajectories of Fetal Adipose Tissue Thickness in Pregnancies After Gastric Bypass Surgery

Trajectories of Fetal Adipose Tissue Thickness in Pregnancies After Gastric Bypass Surgery

A Longitudinal Study of the Antioxidant Barrier and Oxidative Stress in Morbidly Obese Patients after Bariatric Surgery. Does the Metabolic Syndrome Affect the Redox Homeostasis of Obese People?

Impact of Depression on Weight Variation after Bariatric Surgery: A Three-Year Observational Study

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