Obesity portends increased morbidity and earlier recurrence following liver transplantation for hepatocellular carcinoma

Abstract

These findings indicate that BMI is an important surrogate marker for obesity and portends an increased risk for complications and a poorer oncologic outcome following OLT for HCC.

Are sarcopenia, obesity and sarcopenic obesity predictive of outcome in patients with colorectal liver metastases?

“…35 Others found that obesity influenced major morbidity. 36 Possibly the increased percentage body fat in this population was not as profound as needed to increase morbidity significantly, 33 but just sufficient to increase the physiological reserve and have a positive effect on OS.…”

Donor characteristics and risk of hepatocellular carcinoma recurrence after liver transplantation

“…In addition, although not uniformly, previous data from both experimental and clinical settings have shown that fatty livers are prone to cancer growth and recurrence after oncological liver surgery. Recipient obesity has also been reported to be associated with an earlier and increased risk of HCC recurrence after liver transplantation. In this regard, steatosis may be related to increased post‐transplant cancer recurrence through several mechanisms.…”

Increasing body mass index portends abbreviated survival following pancreatoduodenectomy for pancreatic adenocarcinoma

“…13 Additionally, Mathur et al have demonstrated that obesity is associated with a worse prognosis from hepato-pancreatico-biliary cancers. [17][18][19][20] BMI is commonly used as a marker for obesity. However, it does not distinguish between the distributions of adiposity in the body.…”