Obesity Prevalence and Associated Outcomes in Cardiothoracic Patients: A Single-Centre Experience

Goh, Ruth; Darvall, Jai; Wynne, Rochelle; Tatoulis, James

doi:10.1177/0310057x1604400112

Cited by 3 publications

(1 citation statement)

References 43 publications

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“…In addition, we also identified one unduplicated article from the reference search. In total, 72 studies that examined the impact of adiposity on readmission and all‐cause mortality following CABG were included in the review …”

Section: Resultsmentioning

confidence: 99%

Adiposity in relation to readmission and all‐cause mortality following coronary artery bypass grafting: A systematic review and meta‐analysis

et al. 2019

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Summary This study systemically reviewed evidence linking adiposity to readmission and all‐cause mortality in post‐coronary artery bypass grafting (CABG) patients. Keyword/reference search was performed in PubMed, Web of Science, CINAHL, and Cochrane Library for articles published before June, 2018. Eligibility criteria included study designs: experimental/observational studies; subjects: adult patients undergoing CABG; and outcomes: hospital/clinic readmissions, and short‐term (≤30 days) and mid‐to‐long‐term (>30 days) all‐cause mortality. Seventy‐two studies were identified. Meta‐analysis showed that the odds of post‐CABG readmission among patients with overweight was 30% lower than their normal‐weight counterparts and the odds of mid‐to‐long‐term post‐CABG mortality among patients with overweight were 20% lower than their normal‐weight counterparts. In contrast, no difference in post‐CABG readmission rate was found between patients with obesity and their nonobese counterparts; no difference in short‐term or in‐hospital post‐CABG mortality rate was found between patients with overweight or obesity and their normal‐weight counterparts; and no difference in mid‐to‐long‐term post‐CABG mortality rate was found between patients with obesity and their normal‐weight counterparts. In conclusion, patients with overweight but not obesity had a lower readmission and mid‐to‐long‐term mortality rate following CABG relative to their normal‐weight counterparts. Preoperative weight loss may not be advised to patients with overweight undergoing CABG.

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Section: Resultsmentioning

confidence: 99%

Adiposity in relation to readmission and all‐cause mortality following coronary artery bypass grafting: A systematic review and meta‐analysis

et al. 2019

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Obesity, acute kidney injury and outcome of critical illness

Schiffl

Lang

2016

Int Urol Nephrol

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Acute kidney injury is a heterogeneous clinical syndrome encompassing a spectrum of risk factors and acute insults, occurring in multiple settings and affecting both short-term and long-term outcomes. Obesity has become an epidemic. The available literature suggests that AKI is common in critically ill surgical or medical obese patients and that obesity is a novel risk factor for this acute renal syndrome. The pathophysiology of obesity-associated AKI is not completely understood. Obesity-related factors combined with the burden of other comorbidities in elderly obese patients may interact with known precipitating factors such as hypotension, nephrotoxins or sepsis and increase the susceptibility of this population to AKI. Whether or not obesity may counterintuitively be protective and associated with better survival of critically ill patients with AKI ("reverse epidemiology") is a subject for debate. Further investigations exploring the role of novel biomarkers and optimal management are needed urgently.

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Übergewicht und Nierenerkrankungen – renale Risiken einer „Epidemie“

Schiffl¹,

Lang²

2017

Dtsch med Wochenschr

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Overweight and obesity are widespread in the German population, affecting not only adults but also a significant number of children and adolescents. The risk to develop chronic kidney disease is markedly increased in overweight or adipose children, adolescents and adults.Overweight and obesity induced risk factors have a direct impact on the development of chronic renal disease (obesity-associated focal segmental glomerulosclerosis). They accelerate the progression of coexistent nephropathies (diabetic or hypertensive nephropathy, primary glomerulonephritides) and are independent risk factors for the development of acute kidney injury in critically ill patients.Obesity induced nephropathies are basically preventible. Marked weight reduction, normoglycemia and control of hypertension may contribute to an improved glomerular filtration rate and/or reduced proteinuria in early stages of renal damage.The prevalence of kidney diseases in Germany is 13 % and estimated 80 000 patients need renal replacement therapy. In order to avoid a further rapid increase in numbers, preventive measures should be enforced more rigorously.It is necessary to raise the awareness of the negative consequences of obesity in the general public, to motivate the public to adopt a healthier lifestyle and to install nephrological surveillance to contain the obesity "epidemic".

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Obesity Prevalence and Associated Outcomes in Cardiothoracic Patients: A Single-Centre Experience

Cited by 3 publications

References 43 publications

Adiposity in relation to readmission and all‐cause mortality following coronary artery bypass grafting: A systematic review and meta‐analysis

Adiposity in relation to readmission and all‐cause mortality following coronary artery bypass grafting: A systematic review and meta‐analysis

Obesity, acute kidney injury and outcome of critical illness

Übergewicht und Nierenerkrankungen – renale Risiken einer „Epidemie“

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