Abstract-In this letter, we investigate the removal of multiple access interference and optical beat noise from a two-channel optical system that simulates the output from a time-spread optical code-division multiple access system operating at a data rate of 100 Mb/s. Both noise sources were removed using a saturable absorber semiconductor optical amplifier two-photon absorption receiver structure. Experimental results show error-free operation when all three devices are used together.Index Terms-Multiple access interference, optical beat noise, saturable absorber (SA), semiconductor optical amplifier (SOA), two-photon absorption (TPA).