FPN (Feature Pyramid Network) and transformer-based target detectors are commonly employed in target detection tasks. However, these approaches suffer from design flaws that restrict their performance. To overcome these limitations, we proposed TIG-DETR (Texturized Instance Guidance DETR), a novel target detection model. TIG-DETR comprises a backbone network, TE-FPN (Texture-Enhanced FPN), and an enhanced DETR detector. TE-FPN addresses the issue of texture information loss in FPN by utilizing a bottom-up architecture, Lightweight Feature-wise Attention, and Feature-wise Attention. These components effectively compensate for texture information loss, mitigate the confounding effect of cross-scale fusion, and enhance the final output features. Additionally, we introduced the Instance Based Advanced Guidance Module in the DETR-based detector to tackle the weak detection of larger objects caused by the limitations of window interactions in Shifted Window-based Self-Attention. By incorporating TE-FPN instead of FPN in Faster RCNN and employing ResNet-50 as the backbone network, we observed an improvement of 1.9 AP in average accuracy. By introducing the Instance-Based Advanced Guidance Module, the average accuracy of the DETR-based target detector has been improved by 0.4 AP. TIG-DETR achieves an impressive average accuracy of 44.1% with ResNet-50 as the backbone network.