“…A digital environment generally also facilitates image data management, communication, and navigation, both locally during a review session and globally across department and hospital boundaries. Significant recent advances in the conceptual development of Picture Archiving and Communication Systems (PACS) [1]- [4], the introduction of the DICOM standard [5] [6] designed to facilitate image data interchange among clinical institutions, and the growing number of commercial PACS (e.g., Shared Vision from ImageLabs, Burlington, MA; VRS and Allegro by ISG, Toronto, Canada; and Bscan from GLP Rochester, NY), and public domain PACS (such as OSIRIS [7] [8]) are clear evidence that digital image review technologies are in the process of replacing traditional film-based procedures. However, when designing clinical software for image management, display, and enhancement, one has to take into account that the clinician may be inexperienced in the use of modern computer workstations.…”