Objective and subjective sleep disturbances in patients with systemic lupus erythematosus

Valencia‐Flores, Matilde; Resendiz, Montserrat; Castaño, Violeta A.; Santiago, Victoria; Campos, Rosa M.; Sandino, Sayonara; Valencia, Xavier; Alcocer, Jorge; Ramos, Guillermo; Bliwise, Donald L.

doi:10.1002/1529-0131(199910)42:10<2189::aid-anr21>3.0.co;2-v

Cited by 94 publications

(74 citation statements)

References 8 publications

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“…The use of prednisone in the present study was associated with sleep disturbances, although other studies have not shown a relationship between use of corticosteroids and sleep disturbance in SLE (4,5,32). Although fewer patients in our sample were receiving corticosteroids, a greater proportion were taking higher doses of corticosteroids compared with previous studies (4,5,32), which may partially explain our results.…”

Section: Discussioncontrasting

confidence: 75%

“…A relationship between depressed mood and respiratory disturbances during sleep in SLE patients using polysomnographic data has previously been demonstrated (4). The relationship between sleep disturbances and depressed mood has also been shown in epidemiologic studies of sleep in the general population (33)(34)(35), and with other medical patients (i.e., arthritis, chronic pain) (36 -38).…”

Section: Discussionmentioning

confidence: 73%

“…ValenciaFlores et al (4) evaluated polysomnographic data in 14 SLE patients and found that sleep was characterized by respiratory (50%) and movement (50%) disorder. Disease activity was associated with more sleep fragmentation and with less sleep efficiency.…”

Section: Introductionmentioning

confidence: 99%

“…However, limitations of these studies include small sample sizes (ranging from 14 -48 patients) (3)(4)(5) and the use of different sleep assessments (some unstandardized) (3). Although sleep disturbance is believed to be multidetermined (1), the specific factors involved and their relative importance in SLE remains virtually unknown.…”

Section: Introductionmentioning

confidence: 99%

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Determinants of sleep quality in women with systemic lupus erythematosus

Costa

Bernatsky

Dritsa

et al. 2005

Arthritis & Rheumatism

130

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Objective. To characterize sleep complaints in women with systemic lupus erythematosus (SLE) and to identify correlates of sleep quality. Methods. Sleep quality in 100 women with SLE was assessed using the Pittsburgh Sleep Quality Index (PSQI). Participants completed standardized questionnaires assessing depressed mood, leisure time physical activity, functional disability, and pain severity. A clinical examination determined disease activity, cumulative damage, and whether patients fulfilled the American College of Rheumatology criteria for fibromyalgia. A series of hierarchical multiple regressions were computed. Results. The mean ؎ SD global PSQI score was 6.98 ؎ 4.03, with moderate to severe sleep impairment reported by 56% of the sample. The first model testing the importance of demographic factors was not statistically significant. In the disease-related model, the use of prednisone and functional disability both contributed to poor sleep quality (P < 0.001). The addition of level of exercise participation to the demographic set significantly added to the model (P ‫؍‬ 0.001). Depression significantly added to the demographic set, explaining 29% of the variance (P < 0.0001). When these variables, along with disease related variables, were simultaneously regressed on the PSQI Global Score, only depressed mood appeared as a significant independent determinant of global sleep quality (P < 0.001). However, the point estimates for the Beta coefficients were consistent with effects for lack of exercise and prednisone use. Conclusion. A significant proportion of women with SLE suffer from poor sleep quality. The findings suggest that depressed mood, prednisone use, and lack of exercise contribute to decreased overall sleep quality.

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Section: Discussioncontrasting

confidence: 75%

Section: Discussionmentioning

confidence: 73%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Determinants of sleep quality in women with systemic lupus erythematosus

Costa

Bernatsky

Dritsa

et al. 2005

Arthritis & Rheumatism

130

View full text Add to dashboard Cite

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“…Individuals with systemic lupus erythematosus (SLE) often contend with fatigue (1,2), pain (3), sleep disturbances (2,4), depression (1,3,5), and anxiety (6,7). Given the unpredictability of SLE, the severity of symptoms, and the fact that it affects young adults (8,9), a diminished ability to fulfill social roles within the family is expected; however, the extent of this social role disruption and potential impact on disease outcomes and psychological well-being may not be fully appreciated.…”

Section: Introductionmentioning

confidence: 99%

Assessment of health‐related family role functioning in systemic lupus erythematosus: Preliminary validation of a new measure

Hassett

Radvanski

et al. 2012

Arthritis Care & Research

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Objective. Individuals with systemic lupus erythematosus (SLE) often experience symptoms that affect family relationships, which are important components of quality of life. To assess the impact of SLE on family role functioning, we developed a 6-domain (Fatigue, Activity participation, Mental health, Isolation, Love and intimacy, and You/fulfilling family roles [FAMILY]) measure. The objectives of this study were to pilot test and achieve preliminary validation for the SLE-FAMILY questionnaire.Methods. This was a 3-phase study. In phase 1 (development), domains were identified and items were generated for evaluation. During phase 2 (pilot test), a pilot test was conducted to assess the performance of candidate items. In phase 3 (initial validation), 52 individuals with SLE completed questionnaires, including the 6-item SLE-FAMILY. Data were analyzed for internal consistency reliability, and validity was assessed using correlations between the SLE-FAMILY questionnaire and well-validated measures. Results. The SLE-FAMILY had good test-retest reliability (0.82) and internal consistency (0.67). Reliability analysis of individual items revealed weakness in the performance of item 5. We reviewed raw data and determined that 9 individuals likely overlooked the reverse scoring of item 5, thus explaining its poor reliability. When these 9 individuals were excluded from analysis, Cronbach's alpha increased to 0.71, while test-retest reliability remained acceptable (0.75). Spearman's rho correlations supported the validity of the SLE-FAMILY measure. A pilot test of the SLE-FAMILY questionnaire without the reverse-scored item was conducted; results suggested that the modified version is superior to the initial form. Conclusion. The SLE-FAMILY questionnaire is a promising new instrument for robust measurement of family role functioning.

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Sleep Disorders and Systemic Disease

Louis

2013

Neurological Disorders Due to Systemic Disease

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Objective and subjective sleep disturbances in patients with systemic lupus erythematosus

Abstract: There is an enhanced presence of sleep disorders in patients with SLE. The most frequent primary sleep disorders are respiratory and movement disorders.

Cited by 94 publications

References 8 publications

Determinants of sleep quality in women with systemic lupus erythematosus

Determinants of sleep quality in women with systemic lupus erythematosus

Assessment of health‐related family role functioning in systemic lupus erythematosus: Preliminary validation of a new measure

Sleep Disorders and Systemic Disease

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