The shape of the hadronic form factor f+(q 2 ) in the decay D 0 → K − e + νe has been measured in a model independent analysis and compared with theoretical calculations. We use 75 fb −1 of data recorded by the BABAR detector at the PEPII electron-positron collider. The corresponding decay branching fraction, relative to the decay D 0 → K − π + , has also been measured to be RD = BR(D 0 → K − e + νe)/BR(D 0 → K − π + ) = 0.927 ± 0.007 ± 0.012. From these results, and using the present world average value for BR(D 0 → K − π + ), the normalization of the form factor at q 2 = 0 is determined to be f+(0) = 0.727 ± 0.007 ± 0.005 ± 0.007 where the uncertainties are statistical, systematic, and from external inputs, respectively.