The physics of accretion disks is of fundamental importance for understanding of a wide variety of astrophysical sources that includes protostars, X-ray binaries, and active galactic nuclei. The interplay between hydrodynamic flows and magnetic fields and the potential for turbulence-producing instabilities is a topic of active research that would benefit from the support of dedicated experimental studies. Such efforts are in their infancy, but in an effort to push the enterprise forward we propose an experimental configuration which employs a modified cylindrical wire array Z-pinch to produce a rotating plasma flow relevant to accretion disks. We present three-dimensional resistive magnetohydrodynamic simulations which show how this approach can be implemented. In the simulations, a rotating plasma cylinder or ring is formed, with typical rotation velocity ∼30 km s −1 , Mach number ∼4, and Reynolds number in excess of 10 7 . The plasma is also differentially rotating. Implementation of different external magnetic field configurations is discussed. It is found that a modest uniform vertical field of 1 T can affect the dynamics of the system and could be used to study magnetic field entrainment and amplification through differential rotation. A dipolar field potentially relevant to the study of accretion columns is also considered.