Observation of sound-induced corneal vibrational modes by optical coherence tomography

Abstract

Abstract:The mechanical stability of the cornea is critical for maintaining its normal shape and refractive function. Here, we report an observation of the mechanical resonance modes of the cornea excited by sound waves and detected by using phase-sensitive optical coherence tomography. The cornea in bovine eye globes exhibited three resonance modes in a frequency range of 50-400 Hz. The vibration amplitude of the fundamental mode at 80-120 Hz was ~8 µm at a sound pressure level of 100 dB (2 Pa). Vibrography allows the visualization of the radially symmetric profiles of the resonance modes. A dynamic finite-element analysis supports our observation. ©2015 Optical Society of America

Effects of Thickness on Corneal Biomechanical Properties Using Optical Coherence Elastography

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Corneal cross‐linking as a treatment for corneal dystrophy with secondary bacterial infection in a Friesian horse

“…Optical coherence tomography (OCT) is an important noninvasive imaging tool for corneal diseases in human ophthalmology and widely used in animal research . It generates cross‐sectional images providing information with resolutions approaching that of histopathology .…”

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Assessment of the influence of viscoelasticity of cornea in animal ex vivo model using air‐puff optical coherence tomography and corneal hysteresis

“…OCE dedicated to the evaluation of the corneal elastic properties includes different mechanical excitation mechanisms. The load may be applied in a contact or noncontact way, for example, by the gonioscopy lens , mechanical indentation , pulsed laser , sound waves , airborne ultrasound and the air puff from the tube or needle . The performance of the OCT‐based elastography has been demonstrated in in vitro corneal tissues , in ex vivo eye models as well as in in vivo studies with patients .…”