Applying time-periodic modulations is routinely used to control and design synthetic matter in quantum-engineered settings. In lattice systems, this approach is explored to engineer band structures with non-trivial topological properties, but also to generate exotic interaction processes. A prime example is density-assisted tunneling, by which the hopping amplitude of a particle between neighboring sites explicitly depends on their respective occupations. Here, we show how densityassisted tunneling can be tailored in view of simulating the effects of strain in synthetic graphene-type systems. Specifically, we consider a mixture of two atomic species on a honeycomb optical lattice: one species forms a Bose-Einstein condensate in an anisotropic harmonic trap, whose inhomogeneous density profile induces an effective uniaxial strain for the second species through density-assisted tunneling processes. In direct analogy with strained graphene, the second species experiences a pseudo magnetic field, hence exhibiting relativistic Landau levels and the valley Hall effect. Our proposed scheme introduces a unique platform for the investigation of strain-induced gauge fields and their possible interplay with quantum fluctuations and collective excitations.