Observation on distribution of Shigella species in lagos: a report for the period 1985?1988

Ogunsanya, T. I.; Uzoma, K; Odugbemi, T

doi:10.1007/bf00145799

Cited by 2 publications

(2 citation statements)

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“…Escherichia–Shigella is common pathogens, the main transmission paths of which comprise the feces of the infected subject, food, and water containing the bacteria. The pathogen can cause inflammation of the colon mucosa, resulting in symptoms such as abdominal pain, diarrhea, and mucosanguineous stool ( Ogunsanya et al, 1990 ). Therefore, food and water for feeding the musk deer and manure management are indicated as keys to reducing mild diarrhea.…”

Section: Discussionmentioning

confidence: 99%

Comparison Between the Fecal Bacterial Microbiota of Healthy and Diarrheic Captive Musk Deer

Yang

et al. 2018

Front. Microbiol.

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Diarrhea constitutes one of the most common diseases affecting the survival of captive musk deer and is usually caused by an imbalance in intestinal microbiota. Currently, research regarding the structure and function of intestinal microbiota in diarrheic musk deer is lacking. Therefore, in the present study, high-throughput 16S-rRNA gene sequencing was used to analyze the intestinal microbiota in feces of healthy captive musk deer (HMD) (n = 8) and musk deer with mild (MMD) (n = 8), and severe (n = 5) (SMD) diarrhea to compare the difference in intestinal microbiota of musk deer under various physiological conditions. The results showed that the diversity of HMD fecal microbiota was significantly higher than that of the two diarrhea samples. β Diversity results indicated that there were extremely significant differences in bacterial communities between the HMD sample and the MMD and SMD samples. However, no significant difference was found between the two diarrhea samples. LefSe analysis showed that the degree of intestinal physiological dysfunction in musk deer was correlated with the types of major pathogens. The main pathogen in the MMD group is Escherichia–Shigella, whereas Fusobacterium is the main pathogen in the SMD group. PICRUSt functional profile prediction indicated that the intestinal microbiota disorder could also lead to changes in the abundance of genes in metabolic pathways of the immune system. Altogether, this study provides a theoretical basis for the exploration of treatments for diarrhea in captive musk deer, which is of considerable significance to the implementation of the musk deer release into the wild program.

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Section: Discussionmentioning

confidence: 99%

Comparison Between the Fecal Bacterial Microbiota of Healthy and Diarrheic Captive Musk Deer

Yang

et al. 2018

Front. Microbiol.

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“…When specific to the genus level, Staphylococcus is a well-known pathogenic bacterium recently identified to colonize inside the intestinal tracts of hospitalized patients, which may be an important reason for various gastrointestinal disorders such as diarrhea ( 29 , 43 ). Similarly, Escherichia-Shigella is a common pathogen to trigger inflammation of the colon mucosa, leading to symptoms such as diarrhea, abdominal pain, and mucosanguineous stool ( 44 ). In the present study, we reported a repressive effect of mCRAMP in the colonization of Staphylococcus and Escherichia-Shigella in mice intestines ( Supplementary Table S3 ).…”

Section: Discussionmentioning

confidence: 99%

Alterations in Intestinal Microbiota Composition in Mice Treated With Vitamin D3 or Cathelicidin

Wan

Zhao

et al. 2021

Front. Oncol.

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Gut microbiota is a complex aggregation of microbial organisms, which offers diverse protective benefits to the host. Dysbiosis of intestinal microbiota is frequently associated with many diseases. Vitamin D3 (VD), which was originally associated with bone health, also possesses antimicrobial activities and can act through antimicrobial peptide. Cathelicidin is a type of antimicrobial peptide in host to maintain the balance of gut microbiome. Our current study sought to evaluate the protective effect of VD and cathelicidin in mice intestines by administration of VD or mCRAMP-encoding L. lactis. We herein provided a comprehensive profile of the impact of VD and mCRAMP on gut microbiota using 16S rRNA sequencing, followed by bioinformatics and statistical analysis. Our results revealed an increased richness of bacterial community in mice intestines due to VD administration. Moreover, we showed a beneficial effect of VD and mCRAMP by enhancing the colonization of bacterial taxa that are associated with protective effects to the host but repressing the propagation of bacterial taxa that are associated with harmful effects to the host. Various metabolic pathways related to amino acid and lipid metabolism were affected in this process. We further established a bacterial panel as a reliable biomarker to evaluate the efficacy of remodeling the mice gut microbiota by VD and mCRAMP administration. The uncovered effects will deepen the comprehension about the antibacterial mechanisms of VD and mCRAMP and provide new insights for therapeutic implication of them.

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Observation on distribution of Shigella species in lagos: a report for the period 1985?1988

Cited by 2 publications

References 1 publication

Comparison Between the Fecal Bacterial Microbiota of Healthy and Diarrheic Captive Musk Deer

Comparison Between the Fecal Bacterial Microbiota of Healthy and Diarrheic Captive Musk Deer

Alterations in Intestinal Microbiota Composition in Mice Treated With Vitamin D3 or Cathelicidin

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