Brightness variation is an essential feature of quasars, but its mechanism and relationship to other physical quantities are not understood well. We aimed to find the relationship between the optical variability and spectral features to reveal the regularity behind the random variation. It is known that a quasar’s Fe ii/Hβ flux ratio and equivalent width of [O iii]5007 are negatively correlated; this is called Eigenvector 1. In this work, we visualized the relationship between the position on this Eigenvector 1 (EV1) plane and how the brightness of the quasars had changed after ∼10 yr. We conducted three analyses, using a different quasar sample in each. The first analysis showed the relation between the quasars’ distributions on the EV1 plane and how much they had changed brightness, using 13438 Sloan Digital Sky Survey quasars. This result shows how brightness changes later are clearly related to the position on the EV1 plane. In the second analysis, we plotted the sources reported as “changing-look quasars” (or “changing-state quasars”) on the EV1 plane. This result shows that the position on the EV1 plane corresponds to the activity level of each source, and the bright or dim states of them are distributed on the opposite sides divided by the typical quasar distribution. In the third analysis, we examined the transition vectors on the EV1 plane using sources with multiple-epoch spectra. This result shows that the brightening and dimming sources move on a similar path and they reach a position corresponding to the opposite activity level. We also found this trend is opposite to the empirical rule that $R_{\rm {Fe\, \small {II}}}$ positively correlated with the Eddington ratio, which has been proposed based on the trends of a large number of quasars. From all these analyses, it is indicated that quasars tend to oscillate between both sides of the distribution ridge on the EV1 plane; each of them corresponds to a dim state and a bright state. This trend in optical variation suggests that significant brightness changes, such as changing-look quasars, are expected to repeat.