“Observations of Serum Magnesium Levels in Major Burns”

Toppo, Samir; Kamal, Anil. K.; Pratap, Vinay; Kant, Dr.Utkrisht

doi:10.9790/0853-1605042226

Cited by 6 publications

(3 citation statements)

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“…4 So, they had given the magnesium therapy to these cases. They did not find any significant differences on magnesium levels across age and sex groups.…”

Section: Discussionmentioning

confidence: 99%

“…If a person undergoing surgery, his serum magnesium levels must be done and supplementation must be done as the deficiency can be easily corrected and this will also prevent the further deficiency of magnesium postoperatively. 4 With this background present study has been conducted with the aim to study the effect of surgical trauma on serum magnesium levels in the early postoperative period.…”

Section: Introductionmentioning

confidence: 99%

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Effect of surgical trauma on serum magnesium levels in the early postoperative period

et al. 2017

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INTRODUCTIONIn around 300 enzymes, magnesium acts as a cofactor. These enzymes are involved in many biological reactions. These reactions are vital in cell metabolism, they regulate the blood glucose levels, useful in the synthesis of the proteins, also maintain the health of cardiovascular system etc. Bone contains around fifty percent of total body magnesium. And remaining quantity is found in soft tissues. As for other minerals, the levels of magnesium in the body are governed by excretion rate and absorption rate of the magnesium. ABSTRACTBackground: For proper functioning of energy system in the body, magnesium is essential. Deficiency of magnesium leads to hyperactivity of central nervous system and neuromuscular system. During surgery or before surgery or after surgery there can be alterations in the volume of fluid and composition of electrolytes. Objective was to study the effect of surgical trauma on serum magnesium levels in the early postoperative period. Methods: The present hospital based cross sectional study was carried out for a period of one year among 35 cases of surgical stress and 10 normal as control. Institutional ethics committee permission was taken prior to the start of the study. Individual informed consent was noted from each individual patient from both cases and controls. Data was recorded in the pre-designed pre-tested semi structured questionnaire for the present study. Serum magnesium level was assessed in both the groups and compared. Results: It was found that the preoperative magnesium levels were more as compared to postoperative levels among both the types of stress groups but the difference was not found to be statistically significant. (p > 0.05) Among the mild to moderate stress groups, it was found that the preoperative magnesium levels were more as compared to postoperative levels among all the age groups but the difference was not found to be statistically significant. (p > 0.05) Among the severe stress groups, it was found that the preoperative magnesium levels were more as compared to postoperative levels among all the age groups but the difference was not found to be statistically significant. (p > 0.05). Conclusions: Occurrence of postoperative hypomagnesaemia plays a minor role in normal surgical convalescence.

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“…4 So, they had given the magnesium therapy to these cases. They did not find any significant differences on magnesium levels across age and sex groups.…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effect of surgical trauma on serum magnesium levels in the early postoperative period

et al. 2017

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“…A burn takes place when the skin comes into contact with a heat source [ 1 ]. It is associated with tissue injury caused by heat, friction, electricity, radiation, or chemicals [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

The Extent of Burn Injury Significantly Affects Serum Micro- and Macroelement Concentrations in Patients on the First Day of Hospitalisation

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et al. 2022

Nutrients

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Burns exceeding 30% of total body surface area (TBSA) result in considerable hypovolemia coupled with the formation and release of inflammatory mediators, leading to subsequent systemic effects known as burn shock. Because of plasma exudation and the associated losses of large quantities of minerals, severe burns can lead to nutritional deficiencies and consequently disrupt homeostasis and metabolism of the entire body. The study group comprised 62 patients, who were divided into 3 groups according to the severity of burns. Serum samples were tested for concentrations of Ca, Mg, Mn, P, K, Zn, Cu, Fe, Se, Na, Cr, Ni, and Al. The mineral concentrations in serum of patients with burn injuries differ significantly from reference values, but this is not affected by the extent of the body burn. There are statistically significant decreases in serum concentrations of elements important for antioxidant protection (Zn, Cu, Se), and significant increases in the concentrations of toxic elements (Al and Ni), which may aggravate the effects associated with the state of burn shock. The Spearman rank correlation analysis did not reveal any statistically significant relationships between the serum concentrations of Mn, Ni, Al, K, Na, P, Mg, Zn, Se, Cr and the affected body surface area and severity of the burn—the values were at the lower end of the reference range. The obtained results indicate that proper nutrition, including elements replenishment, is extremely important in the recovery process of burn patients and time to nutrition is an important factor affecting patient survival after severe burn.

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