Observations of the Gallbladder and Bile During Pregnancy at Term

Potter, Milton G.

doi:10.1001/jama.1936.02770130020006

Cited by 48 publications

(5 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…v Potter found that bile in similar patients contained a high concentration of cholesterol and a low concentration of bile salts. 10 Friedman et al showed that those women who were entered into the Framingham study and either had gallstones or developed them within the next ten years had more pregnancies at entry than those who showed no evidence of gallstones.~ Ultrasonography is approximately 98 per cen t se nsitive. specific in 94 per cent of cases, and ac~ curate in diagnosing gallstones in 96 per cent.…”

Section: Discussionmentioning

confidence: 99%

Cholecystosonography in pregnancy.

Williamson¹

1984

Journal of Ultrasound in Medicine

View full text Add to dashboard Cite

Ultrasound is currently the modality of choice for examination of the fetus in pregnancy. Pregnancy is felt to be a possible risk factor for the development of gallstones. The purpose of this study was to determine whether obstetric patients sent for ultrasonic evaluation should have a simultaneous ultrasonic examination of the gallbladder to detect asymptomatic gallstones. In this study, 11.3 per cent of 142 patients were found to have gallstones. The authors conclude that cholecystosonography should be performed on pregnant patients sent for ultrasonic examination.

show abstract

Section: Discussionmentioning

confidence: 99%

Cholecystosonography in pregnancy.

Williamson¹

1984

Journal of Ultrasound in Medicine

View full text Add to dashboard Cite

show abstract

“…The increased incidence of cholelithiasis is believed to be related to pregnancy 3 , 4 ) . The cause of gallstone formation in pregnant women has been explained by these two mechanisms : supersaturation of cholesterol in bile and gallbladder hypomotility during pregnancy 5 , 6 ) Studies of gallbladder motility in pregnant women have been limited due to the radiation hazard and invasiveness of the radiologic procedure. At present, the real-time ultrasonography can provide the measurements of gallbladder volume and ejection fraction easily and safely 7 , 8 ) .…”

Section: Introductionmentioning

confidence: 99%

Gallbladder Motility Change in Late Pregnancy and after Delivery

Hahm

Park

Song

et al. 1997

Korean J Intern Med

View full text Add to dashboard Cite

ObjectivesThe incidence of gallstone disease has increased recently in Korea and there seems to be an increased prevalence of gallstones when in association with pregnancy. Although the pathogenesis is incompletely defined, an altered motility of the gallbladder may contribute to the increased risk of gallstones during pregnancy.MethodsWe measured gallbladder volume using real-time ultrasonography to find out the mechanism for the changes of gallbladder motility during late pregnancy. Eighteen pregnant women took the gallbladder ultrasonography during their last trimester of pregnancy and after delivery: gallbladder volume and ejection fraction were calculated in each patient.ResultsFasting gallbladder volumes increased significantly in the last trimester of pregnancy (25.28± 14.26ml) compared with postpartum (17.44±5.82ml) (p<0.05). Gallbladder volumes measured after fatty meals showed more increment in pregnant women (10.13±7.19ml) than in those after delivery (4.34±3.36ml) (p<0.005). A significantly reduced gallbladder ejection fraction was found in the pregnant group (60.56± 18.80%) compared with those after delivery (77.48± 13.37%) (p<0.005).ConclusionGallbladder motility in late pregnancy shows significant impairment compared with that in postpartum. Thus, we suggest that gallbladder hypomotility may occur during late pregnancy, and this impairment of gallbladder motility may play an important role in gallstone formation.

show abstract

“…First, Johnston, Ravdin, Austin & Morrison (1932) observed that absorption by the canine gall-bladder proceeded three times more slowly at night than during the day. Secondly, it was noticed by an obstetrician that the gall-bladder was highly distended in 75 % of pregnant women undergoing Caesarean section (Potter, 1936).…”

mentioning

confidence: 99%