1969
DOI: 10.1007/bf01553033
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Observations on dosage of drugs for anesthesia of domestic animals in temperate and tropical climate

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1973
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“…Ambient thermal con ditions were not considered(107). Exton-Smith(36) warned physicians that the dosage of chlorpromazine, particularly in old patients, should be reduced or discontinued in periods of very cold weather and shortage of heating material.The increased heat loss in cold water has caused severe hypothermia in psychiat ric patients under chlorpromazine treatment during swimming for physical therapy(68).Kriihenmann (73) dealing with anesthesia of large domestic animals in the tropical climate of Khartoum, noticed that in general lower doses of chlorpromazine and promazine were required for horses than in the temperate climate of Zurich. This is in agreement with small animal experiments (9).…”
mentioning
confidence: 99%
“…Ambient thermal con ditions were not considered(107). Exton-Smith(36) warned physicians that the dosage of chlorpromazine, particularly in old patients, should be reduced or discontinued in periods of very cold weather and shortage of heating material.The increased heat loss in cold water has caused severe hypothermia in psychiat ric patients under chlorpromazine treatment during swimming for physical therapy(68).Kriihenmann (73) dealing with anesthesia of large domestic animals in the tropical climate of Khartoum, noticed that in general lower doses of chlorpromazine and promazine were required for horses than in the temperate climate of Zurich. This is in agreement with small animal experiments (9).…”
mentioning
confidence: 99%