Observations on Familial Polycystic Disease of the Kidney

Fergusson, J. D.

doi:10.1177/003591574904201013

Cited by 25 publications

(6 citation statements)

References 19 publications

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“…Earlier workers, for instance Kuster (quoted in Fergusson, 1949) had clearly demonstrated two peaks in the age incidence of polycystic disease of the kidneys: one peak at or soon after birth, the other in middle life. Cairns (1925) realized that there were two different varieties: the 'adult type' and the 'congenital cystic kidney of the fetus or newborn', but he concluded that the latter were '.…”

Section: Interpretation Of Previous Reports Inmentioning

confidence: 98%

“…This was recognized as an hereditary trait at least as early as i 899 by Steiner, and its manifestations in adults have been well described from the clinical, pathological, and genetic viewpoints (Oppenheimer, 1934;Fergusson, 1949;Dalgaard, 1957;Heggo, 1966). It is noteworthy that necropsy series agree that in about one third of the patients with this form of the disease there is associated localized cystic malformation of the liver.…”

mentioning

confidence: 99%

“…It is noteworthy that necropsy series agree that in about one third of the patients with this form of the disease there is associated localized cystic malformation of the liver. Although so well defined in adults, the occurrence of this adult type in children had been recorded only rarely and usually without pathological detail or illustration (Steiner, 1899;Halbertsma, 1932;Savera, 1946;Fergusson, 1949).…”

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confidence: 99%

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Polycystic disease of kidney and liver presenting in childhood.

Blyth¹,

Ockenden²

1971

Journal of Medical Genetics

332

135

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Section: Interpretation Of Previous Reports Inmentioning

confidence: 98%

mentioning

confidence: 99%

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confidence: 99%

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Polycystic disease of kidney and liver presenting in childhood.

Blyth¹,

Ockenden²

1971

Journal of Medical Genetics

332

135

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“…Familial involvement in polycystic disease of the kidneys has been well documented (Dalgaard, 1963;Potter, 1961) and there is ample evidence (Ferguson, 1949) that the disease in adults is inherited as an autosomal dominant trait. Occasional reports of familial medullary sponge kidney have also been published (Copping, 1967).…”

Section: Discussionmentioning

confidence: 99%

Medullary cystic disease of the kidney: its occurrence in two siblings

Handa

Tennant

1968

Postgraduate Medical Journal

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Summary Two cases of medullary cystic disease of the kidney in two siblings are presented. In both siblings there was an insidious onset of azotaemia and anaemia at an early age. The urinalyses were normal except for a trace of proteinuria and persistent low specific gravity. The kidneys were small by radiological studies and this was proved at necropsy. The gross microscopic appearances of the kidneys were consistent with medullary cystic disease. The literature on this subject and current views on the similarities between familial juvenile nephronophthisis and this condition are discussed.

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“…They state further that there is increasing evidence to suggest that in the adult type the majority of the cysts are formed in the course of patent and functioning tubules, unlike the condition found in the infantile form, in which the tubules end blindly. Fergusson (1949) has expressed the view that in the adult form, to which this case might belong, a clear familial history is almost always forthcoming.…”

Section: Figmentioning

confidence: 99%

Calcification in a Polycystic Kidney

Willson-Pepper¹,

Slade

1955

British Journal of Urology

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SUMMARY A case of polycentric kidney occurring in a child aged 7 years is here presented with the following features of special interest:— 1. Diffuse flake calcification throughout the renal parenchyma, leading to a pre‐operative Diagnosis of malignant disease. 2. While largely conforming to the adult type of polycentric renal disease no family incidence Traceable. 3. Histological appearance of calcifying cartilage in the radio‐opaque areas. 4. Histological characteristics of both infantile and adult types of polycentric disease. 5. Hydronephrotic changes and a fully developed collecting system. 6. No definite clinical or radiological evidence of involvement of the remaining kidney. A tentative conclusion is drawn that this case belongs to a very rare group of unilateral cystic disease of the kidneys classified as niulticystic disease.

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Observations on Familial Polycystic Disease of the Kidney

Cited by 25 publications

References 19 publications

Polycystic disease of kidney and liver presenting in childhood.

Polycystic disease of kidney and liver presenting in childhood.

Medullary cystic disease of the kidney: its occurrence in two siblings

Calcification in a Polycystic Kidney

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