Observations on fetal heart rate and fetal biochemistry

Hon, Edward H.; Khazin, Aida F.

doi:10.1016/0002-9378(69)90008-8

Cited by 29 publications

(17 citation statements)

References 14 publications

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“…The third method of selecting normal patients has been to choose those in whom continuous electronic monitoring of the fetal heart rate showed no abnormality. This was the criterion of Hon and Khazin (1969) and of Kubli et af. (1969).…”

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confidence: 89%

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Lack of Agreement on Normal Values for Fetal Scalp Blood

Lumley

McKinnon

Wood

1971

BJOG

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AND SummaryThere are significant differences between authors in the values given for the normal range of pH and blood gases in fetal scalp blood during the first stage of labour. Oxygen tensions show the least agreement. The differences cannot be explained by the ways the normal study group were selected (clinically normal ; normal monitored fetal heart rate; healthy newborn infants) nor by choice of measuring system. Both inaccuracy of measurement and variation in the arterial and venous contributions to scalp capillary blood are probably involved. An alternative way of deriving the normal range is described. This gives 7-25 as the lower limit of normal for pH and 60 mm. Hg as the upper limit of normal for Pco,. Definition of hypoxaemia and therefore discussion of its extent and significance remains impracticable at present. However, the normal human fetus does not appear to be in a state of metabolic acidosis in early labour. 13

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confidence: 89%

“…This was the criterion of Hon and Khazin (1969) and of Kubli et af. This was the criterion of Hon and Khazin (1969) and of Kubli et af.…”

mentioning

confidence: 90%

Lack of Agreement on Normal Values for Fetal Scalp Blood

Lumley

McKinnon

Wood

1971

BJOG

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“…Innocuous fetal heart rate patterns were concomitant with 94 % of pH values greater than 7.25. In similar studies Hon and Khazin (1969) showed a statistically significant increase in fetal base deficit with ominous fetal heart rate deceleration patterns.…”

Section: Fetal Blood Ph and Acid Base Balancementioning

confidence: 69%

Biochemical Tests for the Assessment of Feto-Placental Function

Wilde

Oakey

1975

Ann Clin Biochem

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“…This error is invariably of considerable degree, owing to the * According to SIGGAARD-ANDERSEN'S definition of base deficit, the BD would be calculated at the actual hemoglobin oxygen Saturation [38]. (15)(16)(17)(18)(19)(20) g/100 ml) and for the oxygen Saturation (20-50%), the error caused by ignoring correction for oxygenation amounts to an increase in BD varying between 2.2-4.8 mEq/1 (Fig. 1). (b) The fetal BD is higher than the maternal value In view of the false increase in fetal BD, the materno-fetal BD difference (M/FzIBD) is negative in normal labor, i. e. the fetal BD is higher than the maternal.…”

Section: Authormentioning

confidence: 99%