Observations on the cariostatic effect of calcium sucrose phosphate in a group of children aged 5–17 years*

Harris, Robert S.; Schamschula, R. G.; Gregory, G.; Roots, Miriam; Beveridge, John

doi:10.1111/j.1834-7819.1967.tb02184.x

Cited by 27 publications

(8 citation statements)

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“…Both sodium phytate and calcium su crose phosphate have been put forward as cariostatic food additives, and calcium su crose phosphate has been used in a clinical trial [Harris et al, 1969], Trials of both of these agents in laboratory animals have giv en inconsistent results, however [for refer ences see Grenby, 1973]. The conclusions that may be drawn from these studies in vivo broadly agree with the demineraliza tion findings, although it should be added that earlier types of tests in vitro have shown that both agents can interact with en amel or hydroxyapatite surfaces under cer tain conditions [sodium phytate : Magrill, 1973a, b;Grenby, 1967;calcium sucrose phosphate: Brady et al, 1968].…”

Section: Discussionmentioning

confidence: 99%

Chemical Studies of the Protective Action of Phosphate Compounds against the Demineralization of Human Dental Enamel in vitro

Grenby¹,

Bull²

1980

Caries Res

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Demineralization of enamel by acid buffer and the use of protective agents to combat it were studied by two different techniques, one using intact enamel surfaces and the other powdered enamel. Compared with the acknowledged protective effect of fluoride, calcium glycerophosphate was the most effective phosphate compound. Sodium phytate and calcium sucrose phosphate gave less consistent results. Applied topically, α-glycerophosphate was more effective than β-glycerophosphate. Pretreating the enamel with saliva or a protein solution improved its resistance to the attack of acid buffer but reduced the apparent effectiveness of the protective agents.

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Section: Discussionmentioning

confidence: 99%

Chemical Studies of the Protective Action of Phosphate Compounds against the Demineralization of Human Dental Enamel in vitro

Grenby¹,

Bull²

1980

Caries Res

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“…[ 3 ] Studies proving decrease in the incidence of caries postincorporation of calcium and phosphate into diet paved the way for these to be incorporated into toothpaste. [ 4 ] Further, along with calcium and phosphate, calcium sucrose phosphate (CaSP) addition was studied which also showed synergistic benefits.…”

Section: Introductionmentioning

confidence: 99%

Efficacy of a calcium sucrose phosphate based toothpaste in elevating the level of calcium, phosphate ions in saliva and reducing plaque: A clinical trial

et al. 2018

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Aim:To evaluate and compare the efficacy of “calcium sucrose phosphate” (CaSP) toothpaste (Enafix 5%) with ordinarily used calcium, phosphate-containing toothpaste in elevating the level of calcium, phosphate ions in saliva. Secondary aims were to evaluate substantivity and plaque-reducing ability of CaSP toothpaste.Materials and Methods:Thirty study participants of age group 6–13 years were divided into two groups: Group X (Control group) was made to continue brushing with their regularly used calcium, phosphate-containing toothpaste and Group Y (Test group) was allotted CaSP toothpaste. 1 ml of unstimulated saliva was periodically collected from both groups to determine any alteration in the salivary calcium, phosphate level. Parameters such as substantivity and plaque-reducing ability of CaSP toothpaste were also evaluated. Salivary mineral's intergroup comparison was evaluated by Student's t-test while its intragroup comparison along with the plaque amount variation in Group Y was evaluated by ANOVA and Tukey's post hoc test.Results:Group Y showed an increase in the salivary calcium level though not statistically significant. The increase was pronounced in samples collected on day 1. Group Y showed a consistent level of calcium, phosphate in samples collected immediately and 6 h postbrushing, indicating its substantivity. In addition, Group Y had an impact in reducing the plaque level when the 1st-month plaque score was compared with the 12th-month score.Conclusion:CaSP leads to an increase in the salivary calcium level though it was not statistically significant. Supervised brushing and dietary habits showed a positive effect on both the groups. CaSP toothpaste also showed substantivity and plaque-reducing ability.

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“…Second and third year increments have now been published for a large Australian study which utilized calcium sucrose phosphate added to prepared foods containing carbohydrate (Harris et al 1969). Approximately 4.3 gm.…”

mentioning

confidence: 98%

“…Four studies reported significant reductions in the development of new lesions; the remaining two showed an insignificant reduction. (Stralfors, 1964;Ship and Mickelsen, 1964;Averill and Bibby, 1964;Stookey, Carroll and Muhler, 1967;Finn and Jamison, 1967;Harris et al 1967).…”

mentioning

confidence: 99%

Is dietary phosphate fortification of value as an anticaries agent?

Rowe

1972

Ecology of Food and Nutrition

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Observations on the cariostatic effect of calcium sucrose phosphate in a group of children aged 5–17 years*

Cited by 27 publications

References 0 publications

Chemical Studies of the Protective Action of Phosphate Compounds against the Demineralization of Human Dental Enamel in vitro

Chemical Studies of the Protective Action of Phosphate Compounds against the Demineralization of Human Dental Enamel in vitro

Efficacy of a calcium sucrose phosphate based toothpaste in elevating the level of calcium, phosphate ions in saliva and reducing plaque: A clinical trial

Is dietary phosphate fortification of value as an anticaries agent?

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