A feed trial was conducted for 59 days with juvenile Cherax destructor, mean weight (SE) 0.61 (0.01) g, reared communally and maintained on 16 isoenergetic diets containing crude protein levels of 15, 20, 25, and 30%. For each protein level the fish meal component was replaced by soybean meal to produce diets in which 0, 20, 40, or 60% of the protein originated from soybean meal. Mean percentage weight gain per day ranged from 2.98% (15% protein, 60% soybean meal diet), to 11.75% (30% protein, 40% soybean meal diet). When soybean meal was included at a level of 40-60%, growth rate was reduced relative to that achieved with control diets at 15% and 20% protein levels. In no case did a 20% substitution significantly affect growth over that achieved with controls. A two-way interaction occurred between dietary protein and the level of dietary soybean meal. Feeds of higher protein content appeared to permit higher soybean meal inclusion levels without significantly affecting growth. Increases of 5% protein produced a significant improvement in growth when soybean meal contributed from 40-60% of the total protein. This effect was less pronounced in the control diets and the 20% soybean meal series. The percentages of protein increased and lipid decreased in the carcass as the level of dietary protein increased. A similar effect occurred by increasing the soybean meal substitution level to 60%. An obvious trend in carcass moisture, energy, and ash did not occur. A protein requirement of 30% is apparent when fish meal and soybean meal are included in diets at levels of 20% and 24% respectively. A maximum weight of 14.13 g was recorded for an individual fed the 30% protein, 20% soybean meal diet.