Observations on the Renal Threshold for Ascorbic Acid in Man

Effect of Megadoses of Ascorbic Acid on Serum and Urinary Oxalate

“…The mean plasma level of ascorbate, 3.59 mg%, observed in our volunteers was remarkably higher than the 1.8 mg% plateau level reported by Angel et al (1975), and 1.4 mg% of Faulkner and Taylor (1938). Perhaps the greater intake of 8 g daily in our study could explain these higher levels.…”

Urinary and Plasma Oxalate during Ingestion of Pure Ascorbic Acid: A Re-Evaluation

“…The increase in plasma ascorbate levels during ingestion ( fig. 1) is very close to those previously reported by Hatch et al [1980] during a similar intake of Redoxon and reconfirms a higher plateau level of ascor bate than that reported by Faulkner and Taylor [1938] and Angel et al [1975].…”

The Mechanism of the Excretion of Vitamin C by the Human Kidney 1

“…Hospital, New York City) (Received for publication July 28, 1938) The work of numerous investigators has shown that vitamin C is excreted in the urine (1,2,3,4,5,6,7), and various suggestions have been made as to the relation between the rate of excretion and the concentration in the blood. None of the reported observations, however, are of such a quantitative nature as to afford a description of the mechanism of its excretion.…”