Observations on the Rôle of Tissues in Maintaining the Acid-Base Equilibrium of the Blood

Respiration

“…correspondence between blood and tissue cH changes during am monium chloride acidosis. Katz & Banus (43) found that some types of tissue (e.g., muscle) do not contribute even in small degree to the buffering of fixed acids (hydrochloric acid) liberated into the blood stream. The finding of Rous et al (44) that the cH of "par enchymatous tissue" cells was changed very little, if at all, when mineral acids were added to the blood, whereas "matrix tissues" (e.g., connective tissues and cartilage) did experience such change must invite wonder as to the category in which respiratory neu rones may belong.…”