Observations on the serum phosphatase of cattle and sheep

Clinico-pathological studies on naturally-occurring bovine fascioliasis in the Sudan

“…However, in a small number of cattle infected with the latter species, Obeid (1969) reported increased SGOT, arginase and SAP activities. In the present study, the only significant elevation was recorded in the case of arginase which by virtue of being a liver-specific enzyme with high concentrations in that organ can be used more profitably for assessing the disease than either SAP or SGOT (see Allcroft and Folley, 1941;Garner, 1952;Cornelius, 1970;Wilkinson, 1970). Furthermore, no significant change in the activity of SGPT was found in our infected animals, nor previously in cattle infected with F. hepatica (Ross et al, 1966;Sinclair, 1967) probably due to the low concentration of this enzyme in the bovine liver (Cornelius et al t 1959;Boyd, 1962).…”

Inherited High Alkaline Phosphatase Activity in Cattle Serum

“…The rather narrow activity range in 0 animals and the somewhat wider variations in A animals offer a very probable explanation to the observations by ALLCROFT andFOLLEY (1941) andCROOKSHANK et al (1952) that the phosphatase level remained relatively constant for each animal and that higher levels showed wider fluctuations.…”

Calcium, Phosphorus, and Magnesium Metabolism

“…Allcroft and Folley (1941) found SAP activity to vary between 0.3 and 114.3 and between 3.0 and 166.1 King-Armstrong units/dl in apparently normal cows and ewes, respectively. Alkaline phosphatase is normally found in the bile, and SAP activity is increased in obstructive jaundice.…”

“…This finding has been repeatedly confirmed. Allcroft (1947a) noted that hypocalcemia was present in 76% of 406 clinical cases of hypomagnesemia. Of the 90 cows, only 1 had a serum Mg level higher than 2.0 mg/dl (0.8 mmole/liter), 38 showed levels between 1.1 and 2.0 mg/dl (0.5 and 0.8 mmole/liter), while 51 cows, almost 60%, had serum Mg levels below 1.1 mg/dl (0.5 mmole/liter).…”

“…The final insult that precipitates clinical symptoms of hypomag nesemic tetany in an already susceptible animal may be ( 1 ) a suddenly reduced feed intake (Halse, 1958b;Herd, 1966), (2) adverse weather (Allcroft, 1947b), (3) estrus (Swan and Jamieson, 1956), (4) oral application of relatively high doses of Na 2 HP0 4 , Na 2 S0 4 , or both (Dishington, 1965), or (5) sudden reductions in dietary supplies of Mg or sudden change of diet (Dishington and Tollersrud, 1967). Trigger Effect.…”