Observations on Wound Healing in the Horse

Walton, Gill; Neal, PA

doi:10.1111/j.2042-3306.1972.tb03886.x

Cited by 26 publications

(15 citation statements)

References 9 publications

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“…The small number of animals and the differences in age might have influenced the findings. The present study also showed that wounds on the body healed significantly faster than wounds on the limbs, in agreement with earlier clinical and experimental observations (Walton and Neal 1972;Jacobs et al 1984).…”

Section: Discussionsupporting

confidence: 93%

Differences in second‐intention wound healing between horses and ponies: macroscopic aspects

Wilmink

Stolk

Weeren

et al. 1999

Equine Veterinary Journal

110

122

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Summary Second‐intention healing of deep wounds was studied in 5 horses and 5 ponies. Standardised wounds were created on the distal limbs and hind quarters. Wounds on the metatarsi extended onto the metatarsal bone; the depth of the wounds in the femoral biceps muscle was 18 mm. The wound margins were marked by tattoos. Photographs were taken at weekly intervals to determine the wound area. The relative contribution of contraction and epithelialisation to wound closure was quantified by means of the tattoos. Swelling of the limbs was measured; and regularity and aspect of the granulation tissue were semi‐quantitatively scored. Second‐intention wound healing occurred significantly faster in ponies than in horses, and muscle wounds healed significantly faster than metatarsal wounds. These marked differences reflected the greater contribution of contraction to wound healing. Moreover, demarcation was seen earlier and a healthy granulation bed developed more rapidly in ponies, whereas in horses the granulation tissue remained irregular and purulent for longer. Healing of the metatarsal wounds of horses differed markedly from that of all other wounds: these wounds increased to almost twice their original size in the first 2 weeks, exuberant granulation tissue was persistent, epithelialisation started later, and contraction played a minor role in wound closure. Limb swelling was greater in horses than in ponies. Periosteal new bone formation was more extensive, and was active over a longer period in the metatarsal bones of horses than of ponies. From this study it is concluded that second‐intention healing of deep wounds occurs faster in ponies than in horses. This difference can be largely attributed to a more pronounced and faster wound contraction in ponies than in horses. Therefore, attempts to improve second‐intention wound healing in clinical practice should be directed at stimulation of wound contraction.

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Section: Discussionsupporting

confidence: 93%

Differences in second‐intention wound healing between horses and ponies: macroscopic aspects

Wilmink

Stolk

Weeren

et al. 1999

Equine Veterinary Journal

110

122

View full text Add to dashboard Cite

show abstract

“…The results of this experiment confirm observations previously made in other species: the leg wounds of horses heal at a constant speed during the rapid phase of wound closure. [10][11][12][13] The results also demonstrate that the rate of healing is dependent upon the treatment that is applied to the wound. The rate of healing of equine leg wounds (0.56 mm/day) is similar to that reported in limb wounds of humans (0.58 mm/day).s Wounds treated by bandaging or casting following excision of granulation tissue healed at a slower rate than those treated by cryogenic surgery or those left untreated following excision.…”

Section: Discussionmentioning

confidence: 87%

Treatment of Exuberant Granulation Tissue in the Horse Evaluation of Four Methods

et al. 1983

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Four methods of treating granulating wounds on the dorsal aspect of the metacar‐pophalangeal and metatarsophalangeal joints of ponies were evaluated. The following treatments were used: Group 1—excision of the granulation tissue with no further treatment; Group 2—cryosurgery; Group 3—excision of the granulation tissue and pressure bandage; and Group 4—excision of the granulation tissue and immobilization of the limb with a plaster cast. The wounds in Group 1 healed fastest, without producing exuberant granulation tissue and with only moderate scar fibrosis. The wounds in Group 2 healed without producing exuberant granulation tissue but with marked scarring. Wounds in Groups 3 and 4 took longer (p < 0.001) to heal compared to wounds in Groups 1 and 2. Wounds in Groups 3 and 4 produced exuberant granulation tissue, but the resultant scars were the least fibrotic.

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“…Little, however, has been done on the basic mechanics of wound healing from the experimental point of view (Walton and Neal, 1972). Most experimental work has been carried out on pigs, on man and on small laboratory animals (Ordman and Gillman, 1966;Silver, 1971 andWinter andScales, 1963).…”

Section: Department Of Pathology University Of Bristolmentioning

confidence: 99%

(1) Some Factors Affecting Wound Healing

1973

Equine Veterinary Journal

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SUMMARY General factors known to affect wound healing are reviewed. Those most likely to be important in the horse are general nutritional levels and the effects of temperature especially on wounds of the lower parts of the limbs. Some recent developments in the treatment of nonhealing wounds are mentioned. These include the application of “tissue adhesives” based on cyanoacrylate for use in superficial wounds where there has been extensive tissue loss and where epithelialisation is likely to be slow. The value of local application of oxygen to the surface of non‐healing wounds and skin grafts, to encourage rapid epithelial growth is emphasised. The possible role of anti‐collagen antibodies in the delayed healing of burns is mentioned and arising from this a suggestion is made as to a possible rational explanation for the periodic success of the practice of “firing” in the treatment of chronic sprains and bone proliferations. RÉSUMÉ Les principaux facteurs pour influencer la cicatrisation des plaies sont passés en revue. Parmi eux, ceux qui paraissent être plus spécialement importants chez le cheval sont les facteurs nutritionels et ceux en relation avec la température, notamment lorsqu'il s'agit de plaies des extrémités inférieures des membres. Quelques acquisitions récentes dans le traitement des plaies à cicatrisation lente sont indiquées. En particulier, sont mentionnés les pansements adhésifs tissulaires à base de cyanoacrylates pour l'emploi sur les plaies superficielles, lorsqu'il y a eu perte importante de substance de telle manière que l'épitheliumisation est lente. L'utilitee des applications d'oxygène sur la surface des plaies à mauvaise cicatrisation et la valeur des greffes de peau pour accélerer l'épitheliumisation sont soulignées. Le rôle éventuel joué par les substances anticollagènes dans les retards de cicatrisation des brulures est évoqué: à partir de quoi, une hypothèse d'apparence rationnelle pour interprèter l'action souvent heureuse des feux dans le traitement des claquages et des exostoses est formulée. ZUSAMMENFASSUNG Die allgemeinen Faktoren, die die Wundheilung beeinflussen, werden zusammenfassend besprochen. Diejenígen, die beim Pferd am ehesten eine Rolle spielen, sind die Ernährungsbedingungen und die Temperatur, besonders bei Wunden an den tieferen Gliedmassenteilen. Einige neuere Entwicklungen auf dem Gebiet der Behandlung nicht‐heilender Wunden werden erwähnt, einschliesslich der Verwendung von “Gewebsklebstoffen” auf der Basis von Cyanacrylat bei oberflächlichen Wunden mit erheblichem Substanzverlust und wahrscheinlich langsamer Epithelisierung. Der Wert einer lokalen Applikation von Sauerstoff auf die Oberfläche nichtheilender Wunden und von Hauttransplantaten, um eine rasche Epithelisierung zu erreichen, wird hervorgehoben. Die mögliche Rolle von Antikollagen‐Antikörpern in der verzögerten Heilung von Brandwunden wird erwähnt. Darauf bezugnehmend wird der Versuch gemacht, eine vernünftige Erklärung zu finden für die zeitweiligen Erfolge des Brennens in der Behandlung chronische...

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Observations on Wound Healing in the Horse

Cited by 26 publications

References 9 publications

Differences in second‐intention wound healing between horses and ponies: macroscopic aspects

Differences in second‐intention wound healing between horses and ponies: macroscopic aspects

Treatment of Exuberant Granulation Tissue in the Horse Evaluation of Four Methods

(1) Some Factors Affecting Wound Healing

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