The Passivity-Based Control (PBC) is recognized as an effective energy shaping approach to guarantee the asymptotic stability of the whole system by using the passivity property. However, the model-based and sensor-based characteristics limit its development and application. The combination of the PBC and online estimation technique can solve these problems. The purpose of this paper is to propose a controller and an observer, which are designed simultaneously based on Hamiltonian framework and Lyapunov criterion. It leads to the system design without separation of the dynamics of the controller and the observer. The uncertainties in the model and parameters are considered as equivalent voltage and current sources. To reduce the number of sensors, input voltage, output current, and equivalent sources are estimated together. The steady-state error is eliminated by using this estimation technique. The exponential stability of the whole system (converter, controller, and observer) is proved by using a proper Lyapunov function. Simulation and experimental results from a 3 kW 270−350 V DC/DC boost converter with a Constant Power Load (CPL) are performed to confirm the proposed control algorithm. Since the system parameter values may vary with temperature and the equilibrium point, the robustness of the proposed method is verified without and with parameters uncertainties.Index Terms-Large-signal stability, Interconnection and damping assignment passivity-based control (IDA-PBC), portcontrolled Hamiltonian (PCH), microgrid, DC/DC converter, constant power load (CPL), online estimation.