Observer Variation in Histopathological Diagnosis and Grading of Cervical lntraepithelial Neoplasia

Ismail, Sharif I. M. F.; Colclough, Angela B.; Dinnen, J. S.; Eakins, D.; Evans, David M.; Gradwell, E.; O'Sullivan, J P; Summerell, J; Newcombe, Robert G.

doi:10.1097/00006254-199001000-00026

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“…Over the last two decades, research has also focused on automated cancer diagnosis using histopathological images. This is due to the interobserver variability in diagnosis using the traditional manual slide‐viewing method 8,9 . Automated cancer diagnosis would operate using quantitative measures and objective mathematical judgment.…”

Section: Discussionmentioning

confidence: 99%

Identification of components of fibroadenoma in cytology preparations using texture analysis: a morphometric study

Singh

Gupta

2011

Cytopathology

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Section: Discussionmentioning

confidence: 99%

Identification of components of fibroadenoma in cytology preparations using texture analysis: a morphometric study

Singh

Gupta

2011

Cytopathology

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Positive Predictive Rate of Colposcopic Examination of the Cervix Uteri

Hopman

Kenemans

Helmerhorst

1998

Obstetrical & Gynecological Survey

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Study of literature revealed that the positive predictive rate of the colposcopic impression is better as the cervical lesion is more severe. When directed biopsies are taken, the positive predictive rate of colposcopy increases considerably. For microinvasive disease, the positive predictive rate is quite poor, probably because of the absence of characteristic features. Large loop biopsies diagnosed all cases of microinvasive disease missed by directed biopsies, but this technique has the disadvantage of considerable "overtreatment" when integrated in the management of all patients with abnormal cytology. The restrictions of colposcopy are the invisibility of the squamocolumnar junction and observer variability in the assessment of the impression. The levels of agreement among experienced colposcopists are in the same range as those in cytological and histopathological diagnosis. It is concluded that colposcopy is an indispensable tool in the management of premalignant cervical disease, as long as the restrictions of the technique are kept in mind by the colposcopist.

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Observer Variation in Histopathological Diagnosis and Grading of Cervical lntraepithelial Neoplasia

Cited by 2 publications

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Identification of components of fibroadenoma in cytology preparations using texture analysis: a morphometric study

Identification of components of fibroadenoma in cytology preparations using texture analysis: a morphometric study

Positive Predictive Rate of Colposcopic Examination of the Cervix Uteri

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