Obsessive–compulsive disorder in hospitalized patients with chronic schizophrenia

Poyurovsky, Michael; Hramenkov, Sophia; Isakov, Victoria; Rauchverger, Boris; Modai, Ilan; Schneidman, Michael; Fuchs, Camil; Weizman, Abraham

doi:10.1016/s0165-1781(01)00238-4

Cited by 129 publications

(103 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These results indicated that a right-hemispheric brain damage, contrary to a left-hemisphere hypothesis (see Crow, 1990). Another psychomotor disturbance, the obsessive compulsive disorder was found to be frequently occurred in schizophrenics (23.5%), as reported by Poyurovsky et al (2001), who defined obsessions as intrusive, unwanted and repeated thoughts, and compulsions as the performance of repetitive goal-directed rituals clinically indistinguishable from schizophrenic mannerism or posturing. Porto et al (1997) had found a much higher proportion (46%).…”

Section: Psychiatric Disordersmentioning

confidence: 75%

Psychomotor Theory: Mind-Brain-Body Triad in Health and Disease

Tan¹

2007

Neuroquantology

View full text Add to dashboard Cite

In this study I have outlined the grounds of a new theory, to explain the mind-brain-body triad in health and disease. This is the psychomotor theory. First, I have briefly analyzed the historical development of the relationship between mind and brain, which is being discussed since more than a few thousand years. The tight junctions between psychological and motor systems were subjected to a detailed analysis using examples in health and disease. The feedback circuits between mind, brain, and body were shown to occur within the mind-brain-body triad, in normal states, and psycho-neural diseases. It was stated that psychiatric signs and symptoms are coupled with motor disturbances; neurological diseases are coupled with psychological disturbances; changes in cortical and spinal motor-system activity may influence mind-brain-body triad, and vice versa. Accordingly, a psychomotor theory was created to explain the psychomotor coupling in health and disease, stating that, not the mind-brain duality or unity, but the mind-brain-body triad as a functional unit is essential in health and disease, since mind does not end in the brain, but further controls movements, in a reciprocal manner; mental and motor events share the same neural substrate, cortical and spinal motor neurons; mental events emerging from the motoneuronal system is strongly coupled with the unity of the mind-brain-body triad. So, the psychomotor theory rejects the mind-brain duality, instead, advances the unity of the psychomotor system, which will have important consequences in understanding and improving the human mind, brain, and body in health and disease.

show abstract

Section: Psychiatric Disordersmentioning

confidence: 75%

Psychomotor Theory: Mind-Brain-Body Triad in Health and Disease

Tan¹

2007

Neuroquantology

View full text Add to dashboard Cite

show abstract

“…Another psychomotor disturbance, the obsessive compulsive disorder was found to be frequently occurred in schizophrenics (23.5%), as reported by Poyurovsky et al (2001), who defined obsessions as intrusive, unwanted, and repeated thoughts and compulsions as the performance of repetitive goal-directed rituals clinically indistinguishable from schizophrenic mannerism or posturing. Porto et al (1997) had found a much higher proportion (46%).…”

Section: Psychiatric Disordersmentioning

confidence: 75%

The Psychomotor Theory of Human Mind

Tan

2007

International Journal of Neuroscience

View full text Add to dashboard Cite

This study presents a new theory to explain the neural origins of human mind. This is the psychomotor theory. The author briefly analyzed the historical development of the mind-brain theories. The close relations between psychological and motor systems were subjected to a rather detailed analysis, using psychiatric and neurological examples. The feedback circuits between mind, brain, and body were shown to occur within the mind-brain-body triad, in normal states, and psycho-neural diseases. It was stated that psychiatric signs and symptoms are coupled with motor disturbances; neurological diseases are coupled with psychological disturbances; changes in cortico-spinal motor-system activity may influence mind-brain-body triad, and vice versa. Accordingly, a psychomotor theory was created to explain the psychomotor coupling in health and disease, stating that, not the mind-brain duality or unity, but the mind-brain-body triad as a functional unit may be essential in health and disease, because mind does not end in the brain, but further controls movements, in a reciprocal manner; mental and motor events share the same neural substrate, cortical, and spinal motoneurons; mental events emerging from the motoneuronal system expressed by the human language may be closely coupled with the unity of the mind-brain-body triad. So, the psychomotor theory rejects the mind-brain duality and instead advances the unity of the psychomotor system, which will have important consequences in understanding and improving the human mind, brain, and body in health and disease.

show abstract

“…Although, not all studies have found a poorer prognosis in terms of global functioning and illness severity (Rajkumar et al 2008) or more positive and negative symptoms on the PANSS compared with patients without OCD (Byerly et al 2005 ;Poyurovsky et al 2006 ;Rajkumar et al 2008). With the addition of selective serotonin reuptake inhibitors (SSRIs), symptoms such as agitation and psychosis have been observed in schizoobsessives (Lindenmayer et al 1990 ;Zohar et al 1993 ;Berman et al 1995 ;Bermanzohn et al 1997 ;Poyurovsky et al 1999b) suggesting that in this subgroup the symptoms of OCD may be more difficult to treat with pharmacotherapy. Furthermore, Mukhopadhaya et al (2009) reported that schizo-OCD cases treated with SSRIs showed greater levels of extra-pyramidal side effects compared with untreated counterparts.…”

Section: Introductionmentioning

confidence: 99%

The neuropsychology of the schizo-obsessive subtype of schizophrenia: a new analysis

et al. 2009

View full text Add to dashboard Cite

Background. Interest in the neuro-cognitive profile of patients with schizophrenia and co-morbid obsessive compulsive disorder (schizo-OCD) is rising in response to reports of high co-morbidity rates. Whereas schizophrenia has been associated with global impairment in a wide range of neuro-cognitive domains, OCD is associated with specific deficits featuring impaired performance on tasks of motor and cognitive inhibition involving frontostriatal neurocircuitry.Method. We compared cognitive function using the CANTAB battery in patients with schizo-OCD (n=12) and a schizophrenia group without OCD symptoms (n=16). The groups were matched for IQ, gender, age, medication, and duration of illness.Results. The schizo-OCD patients made significantly more errors on a task of attentional set-shifting (ID-ED set-shift task). By contrast, no significant differences emerged on the Stockings of Cambridge task, the Cambridge Gamble Task or the Affective Go/NoGo tasks. No correlation emerged between ID-ED performance and severity of schizophrenia, OCD or depressive symptoms, consistent with neurocognitive impairment holding trait rather than statemarker status. Schizo-obsessives also exhibited a trend toward more motor tics emphasizing a neurological contribution to the disorder. Conclusion.Our findings reveal a more severe attentional set-shifting deficit and neurological abnormality that may be fundamental to the neuro-cognitive profile of schizo-OCD. The clinical implications of these impairments merit further exploration in larger studies.

show abstract

Obsessive–compulsive disorder in hospitalized patients with chronic schizophrenia

Cited by 129 publications

References 27 publications

Psychomotor Theory: Mind-Brain-Body Triad in Health and Disease

Psychomotor Theory: Mind-Brain-Body Triad in Health and Disease

The Psychomotor Theory of Human Mind

The neuropsychology of the schizo-obsessive subtype of schizophrenia: a new analysis

Contact Info

Product

Resources

About