Obsessive-compulsive tendencies are related to indecisiveness and reliance on feedback in a neutral color judgment task

Sarig, Shelly; Dar, Reuven; Liberman, Nira

doi:10.1016/j.jbtep.2011.09.012

Cited by 39 publications

(27 citation statements)

References 47 publications

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“…These performance decrements are possibly due to inefficient strategies that fail at high task demand ( Harkin and Kessler, 2011 ). Furthermore, higher indecisiveness in OCD may add to the generally increased reaction times found in this study ( Sarig et al, 2012 ).…”

Section: Discussionmentioning

confidence: 80%

Neural correlates of working memory deficits and associations to response inhibition in obsessive compulsive disorder

Heinzel

Kaufmann

Grützmann

et al. 2018

NeuroImage: Clinical

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Previous research in patients with obsessive-compulsive disorder (OCD) has indicated performance decrements in working memory (WM) and response inhibition. However, underlying neural mechanisms of WM deficits are not well understood to date, and empirical evidence for a proposed conceptual link to inhibition deficits is missing.We investigated WM performance in a numeric n-back task with four WM load conditions during functional Magnetic Resonance Imaging (fMRI) in 51 patients with OCD and 49 healthy control participants who were matched for age, sex, and education. Additionally, a stop signal task was performed outside the MRI scanner in a subsample.On the behavioral level, a significant WM load by group interaction was found for both accuracy (p < 0.02) and reaction time measures (p < 0.03), indicating increased reaction times as well as reduced accuracy specifically at high WM load (3-back) in patients with OCD. Whole-brain analyses of fMRI-data identified neural correlates of a load-dependent WM decrement in OCD in the supplementary motor area (SMA) and the inferior parietal lobule (IPL). Within the OCD sample, SMA-activity as well as n-back performance were correlated with stop signal task performance.Results from behavioral and fMRI-analyses indicate a reduced WM load-dependent modulation of neural activity in OCD and suggest a common neural mechanism for inhibitory dysfunction and WM decrements in OCD.

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Section: Discussionmentioning

confidence: 80%

Neural correlates of working memory deficits and associations to response inhibition in obsessive compulsive disorder

Heinzel

Kaufmann

Grützmann

et al. 2018

NeuroImage: Clinical

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“…In a series of studies, Rueben Dar et al provided evidence that individuals with OCD have diminished confidence in their decision-making abilities beyond their specific obsessional checking symptoms. 13,14,15 In one study they showed that obsessional persons reported less confidence in their answers to a general knowledge test compared to non-anxious participants, despite equal accuracy. 14 In another study, OCD severity scores were positively correlated with response time in a neutral color judgment task 13 .…”

Section: Ocd and Doubt: Empirical Studiesmentioning

confidence: 99%

Doubt and the decision-making process in obsessive-compulsive disorder

et al. 2016

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The diagnosis of obsessive-compulsive disorder (OCD) is based on the presence of specific symptoms and their consequence in the lives of those that exhibit them. It is likely that these symptoms emerge from a neurocognitive vulnerability in the mental life of the individual which has a basis in neurophysiology. The prominence of doubt/uncertainty/lack of confidence*, in the clinical presentation of many patients suffering from OCD leads to our consideration of the cognitive basis for this phenomenon. In this paper, we propose that OCD emerges from a perturbation in the decision-making process. Specifically, we hypothesize that there is diminished confidence, conviction, or certainty with regard to assimilating the information necessary to reach a decision. Recent advances in the neuroscience of decision-making provide an opportunity to further our understanding of the vulnerability underlying OCD.

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“…Results from several experimental suggest that individuals with OCD gather more evidence, and take more time, in reaching a decision than do comparison groups [13, 14, 15, 39, 40, 41, 42]. This encourages further investigation of the correlations between doubt, on the phenomenological level, and underlying brain structure and function, on the other.…”

Section: Discussionmentioning

confidence: 99%

“…More recently, empirical studies have utilized cognitive paradigms to investigate doubt and indecision, under different levels of uncertainty, in individuals with and without OCD. For example, Sarig and colleagues [13] found positive correlations between obsessive-compulsive symptoms and performance on a color discrimination task, including amount of time required to complete the task, extent of search through the color continuum, and request for feedback. Stern and colleagues [14] found that OCD patients rated themselves as more uncertain than did controls, while accumulating evidence during a decision-making task, under conditions without objective uncertainty.…”

Section: Introductionmentioning

confidence: 99%

An investigation of doubt in obsessive–compulsive disorder

Samuels

Bienvenu

Krasnow

et al. 2017

Comprehensive Psychiatry

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Background Clinicians have long considered doubt to be a fundamental characteristic of obsessive-compulsive disorder (OCD). However, the clinical relevance of doubt in OCD have not been addressed. Methods Participants included 1,182 adults with OCD who had participated in family and genetic studies of OCD. We used a clinical measure of the severity of doubt, categorized as none, mild, moderate, severe, or extreme. We evaluated the relationship between doubt and OCD clinical features, Axis I disorders, personality and personality disorder dimensions, impairment, and treatment response. Results The severity of doubt was inversely related to the age at onset of OCD symptoms. Doubt was strongly related to the number of checking symptoms and, to a lesser extent, to the numbers of contamination/cleaning and hoarding symptoms. Doubt also was related to the lifetime prevalence of recurrent major depression and generalized anxiety disorder; to the numbers of avoidant, dependent, and obsessive-compulsive personality disorder traits; and to neuroticism and introversion. Moreover, doubt was strongly associated with global impairment and poor response to cognitive behavioral treatment (CBT), even adjusting for OCD severity and other correlates of doubt. Conclusions Doubt is associated with important clinical features of OCD, including impairment and cognitive-behavioral treatment response.

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Obsessive-compulsive tendencies are related to indecisiveness and reliance on feedback in a neutral color judgment task

Cited by 39 publications

References 47 publications

Neural correlates of working memory deficits and associations to response inhibition in obsessive compulsive disorder

Neural correlates of working memory deficits and associations to response inhibition in obsessive compulsive disorder

Doubt and the decision-making process in obsessive-compulsive disorder

An investigation of doubt in obsessive–compulsive disorder

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