Obstacles in conducting clinical trials in the Saudi Arabia

Abstract

<p class="abstract"><strong>Background:</strong> Conducting clinical research in accordance with the standards of regulatory authorities and within the guidelines of the good clinical practice (GCP) is a matter of concern. It has been noticed that some increment in the conduction of clinical trials outside USA and European countries in the last two decades. The main objective of this study is to identify the magnitude of some obstacles that affect the conduction of clinical trials in accordance with the GCP.</p><p class="abstract"><strong>Methods:</strong> Developing questionnaire in accordance with the criteria of the GCP would make assessment on how to buildup infrastructure including policy and procedures of the research institution. Recommendation of the study is to perform this questionnaire every other year to assess the progress and development of the research institution.</p><p><strong>Conclusions:</strong> To identify good clinical researchers, what sort of obstacle(s) regarding conducting clinical trials, and from these obstacles how to resolve it and build up infrastructure for the research institution and also to establish the strategic plan for the research institution.</p>

Comparing the use of Arabic decision aid to usual care

“…The missing data in our study may have reduced the power to detect a significant difference in understanding between groups this highlights one of the major challenges encountered in conducting studies in Saudi Arabia. 20 Overall, the DA was well accepted by patients as indicated by the low refusal rate similar to another study carried out on evaluation of a DA for patients with stage IV non-small cell lung cancer. 21 However, a significant challenge in the continued use of a DA is including the most current evidence, particularly when there are fast advances and changes in cancer treatment modalities.…”