Obstetric Aspects of the Ehlers-Danlos Syndrome

Urogenital and pelvic complications in the Ehlers‐Danlos syndromes and associated hypermobility spectrum disorders: A scoping review

“…Table summarizes the design and publication date characteristics of the 105 included studies . Studies consisted of case reports/series (N = 62, 60%) and observational studies (N = 43, 40%), including cross sectional (N = 29), case‐controlled (N = 12), and cohort (N = 2) designs.…”

“…Lind and Wallenburg found post‐partum hemorrhage in 18.8% of births among EDS patients, vs 7% in a general population group. Several small studies reported rates in EDS patients between 10% and 16.7%, with one reporting a combined intra and post‐partum hemorrhage rate of 19.4%. One retrospective cohort study reported a rate of 4.8% from 747 pregnancies, however it was unclear how post‐partum hemorrhage was defined and occurrence was self‐reported by patients.…”

Post partum haemorrhage secondary to Marfan's disease of the uterine vasculature

“…In a small review of women with Marfan's syndrome, profuse post postpartum haemorrhage was reported in four out of eleven women, two requiring transfusion, compared to one out of eight controls (Pyeritz 1981). Similarly, there appears to be an increased risk of post partum haemorrhage with Ehlers Danlos syndrome (Beighton 1969; McKusick 1972). Unfortunately, in neither series was histological examination possible.…”

An unusual ankle injury

“…Beighton's score was zero. 1 A preliminary diagnosis of a medial ankle dislocation was made and immediate closed reduction was performed in the Emergency Department. Closed reduction took precedence over radiological investigation of the injury since any delays in the restoration of normal anatomy could potentially compromise the integrity of the overlying skin and also increase the risk of neurovascular damage.…”