Obstetric outcomes in pregnant women with and without depression: population-based comparison

Abstract

This study used insurance claims data to evaluate obstetric outcomes in pregnant women with and without depression because population study for Asian women on the issue is limited. We identified 5,064 women with depression at pregnancy in 2005–2013, and 20,024 pregnant women without depression, frequency matched by age, pregnant year and parity. Obstetric events during pregnancy and deliveries were evaluated. The depression group had more events than comparisons for hyperemesis (39.3 vs. 35.5%), abortion (3.3 vs. 2.6%), malpresentation (12.3 vs. 10.3%), C-section (40.2 vs. 34.6%) and intrauterine fetal demise (0.7 vs. 0.4%); risks of these events were significant for childbearing depressed women, not for the 35+ years subgroup. These incidences were higher in depressed women taking antidepressant than those without the medication, but were significant in childbearing depressed subgroup for hyperemesis and C-section with odds ratios of 1.18 (95% confidence intervals (CI), 1.02–1.36) and 1.29 (95% CI, 1.11–1.49), respectively. Incident preterm and low birth weight births were also higher in the depression group than in comparisons, but weren’t significant. In conclusion, women with depression during pregnancy may develop more adverse events than comparisons and are more likely to have a C-section delivery.

Acceptability and Perceived Benefits of Exercise Among Pregnant and Postpartum Women Seeking Psychiatric Care

“…Depression and anxiety during the perinatal period are associated with high levels of maternal distress and functional impairment, as well as with poor medical outcomes. 1 For example, pregnant women with elevated depression require antenatal medical hospitalization more often than non-depressed women, 2 and they have a higher likelihood of delivering preterm and low birth-weight infants. 3 Women with antenatal depression are also more likely to experience comorbid health problems such as obesity, 4 pre-eclampsia, 5 gestational diabetes, 6 and prenatal hypertension 7 -problems that can persist beyond the perinatal period.…”

Women’s Mental Health as a Factor Associated with Exclusive Breastfeeding and Breastfeeding Duration: Data from a Longitudinal Study in Greece

“…All women and their partners that attended the Day Center's psychosocial health intervention were offered the following services during pregnancy and up until the 1st year postpartum: (a) A Midwifery-led Antenatal Educational Program called "Preparation for Labor and Parenthood" (8)(9)(10)(11)(12) The participants' demographic data, as well as their medical, social, and psycho-emotional history, were recorded by a midwife before the start of the psychosocial health intervention (approximately between the 18th and 22th gestation week) and after their oral and written consent had been obtained. Demographic data included the mother's age, educational level, marital status, financial level, and religious beliefs.…”

“…These symptoms may not have been recognized or diagnosed by the woman herself, her family, or a specialist. Perinatal mental health disorders are among the most common morbidities of pregnancy and the postnatal period and seem to have a negative effect on perinatal care and birth outcomes [ 11 , 12 , 13 ] and on the cognitive, social, and emotional development of the child [ 14 , 15 , 16 , 17 ].…”

Gestational exposure to antidepressants and risk of seizure in offspring: A systematic review and meta-analysis

“…However, the review did not conduct a meta-analysis and also did not thoroughly evaluate different methodological issues in particular confoundings that could affect the interpretation of the apparent association of some studies. With antidepressants are still often prescribed to expecting mothers with depression (Payne and Meltzer-Brody 2009), inconsequential adverse outcomes without long-term effects on offspring can lead to unnecessary or even inappropriate cessation (Huang et al 2017) that could lead to the deterioration of maternal psychiatric conditions and finally may cause poor delivery or neonatal outcomes. (Huang et al 2017) In view of such a complex dilemma, we conducted a systematic review and meta-analysis on the association between antidepressant use during pregnancy and the risk of neonatal and childhood seizures.…”