Obstetric, Perinatal Outcome and Follow Up of Children Conceived from Cryopreserved Oocytes

Oocyte and Ovarian Tissue Cryopreservation: Indications, Techniques, and Applications

“…22 All other children appear healthy. 22,110 Data are more limited on children conceived from vitrified oocytes, and therefore the endorsement of this technique instead of slow cryopreservation would be premature despite the perceived advantages of oocyte vitrification. Pregnancies and births achieved from cryopreserved immature oocytes at the GV stage have been reported, but numbers are few and are without long-term follow-up data.…”

Ovarian tissue and oocyte cryopreservation

“…The incidence of chromosomal abnormalities in human embryos obtained from cryopreserved oocytes was no different from that of control embryos using fluorescence in-situ hybridization (47). One recent follow-up of 13 children resulting from cryopreserved oocytes failed to reveal any abnormalities in karyotype, mean age at delivery, mean birth weight, or organ formation (48). In another 3-year follow-up study of 16 children born after oocyte cryopreservation, one case of ventricular septal defect was noted (49).…”

Ovarian tissue and oocyte cryopreservation

“…The incidence of chromosomal abnormalities in human embryos obtained from cryopreserved oocytes was no different from that of control embryos using fluorescence in-situ hybridization (47). One recent follow-up of 13 children resulting from cryopreserved oocytes failed to reveal any abnormalities in karyotype, mean age at delivery, mean birth weight, or organ formation (48). In another 3-year followup study of 16 children born after oocyte cryopreservation, one case of ventricular septal defect was noted (49).…”