Obstructive laryngeal schwannoma in a young female

Chiu, Chang-Chieh; Chou, Shah‐Hwa; Wu, Chun‐Chieh; Liang, Peir‐In; Lee, Ka–Wo

doi:10.1186/s12957-014-0433-1

Cited by 9 publications

(7 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Among the 479 articles resulting from our literature search, 60 primary research papers fulfilled our criteria ( Figure 1 ), providing a total of 74 laryngeal schwannoma patients for combined analysis ( Table 1 and Supplemental Tables S1 and S2, available in the online version of the article). 2-61 The included studies consisted primarily of single case reports (n = 55), 4 reports of 2 cases, and 1 larger case series of 11 patients. The mean age at diagnosis was 43.4 years, with women presenting at a later age compared with men (47.3 years vs 32.8, P < .05).…”

Section: Resultsmentioning

confidence: 99%

Diagnosis and Treatment of Laryngeal Schwannoma: A Systematic Review

Tulli

Bondi

Smart

et al. 2017

Otolaryngol.--head neck surg.

View full text Add to dashboard Cite

Objective This review summarizes the clinical features, diagnostic workup, and surgical treatment of laryngeal schwannoma with the aim of providing guidance for the management of this rare disease. The collated data allowed the statistical testing of several hypotheses, including the efficacy of endoscopic vs open surgical intervention and the usefulness of preoperative biopsy. Data Sources PubMed, Google Scholar, Cochrane, and SCOPUS. Review Methods Basic epidemiological and clinical presentation data were collated together with details of diagnostic image modality, lesion attributes, and the use of preoperative biopsy. Surgical approach to intervention and outcome was also collated and simple statistical analyses applied. Results The 60 original articles selected provided a combined cohort of 74 patients for review. The combined data revealed that schwannoma with pedunculated morphology were always safely removed by endoscopic resection regardless of size and should be treated as a separate entity. Of the nonpedunculated schwannoma, larger tumors were more likely to undergo an open approach, which in turn was associated with higher rates of tracheotomy and postoperative vocal fold paralysis. The small cohort did not reveal a significant association between surgery type and persistent disease. Interestingly, the data revealed a significant association between the use of incisional biopsy and persistent disease. Cases exhibiting extralaryngeal extension of the lesion were shown to exclusively belong to patients with neurofibromatosis/schwannomatosis syndromes. Conclusions Taken together, these findings suggest that incisional biopsy should be avoided, and given the benign nature of the pathology, the least invasive radical approach should be employed.

show abstract

Section: Resultsmentioning

confidence: 99%

Diagnosis and Treatment of Laryngeal Schwannoma: A Systematic Review

Tulli

Bondi

Smart

et al. 2017

Otolaryngol.--head neck surg.

View full text Add to dashboard Cite

show abstract

“…Schwannoma originates from perineural Schwann cells, whereas neurofibroma originates from perineural fibrocytes. 1 Although schwannoma grows extrinsically and eccentrically away from the parental nerve fascicles, neurofibroma is typically entwined with the parental nerves. 3 Thus, surgical separation of the schwannoma from the nerve is theoretically possible, but this is not applicable to neurofibroma.…”

Section: Discussionmentioning

confidence: 99%

“…Benign neurogenic tumors in the larynx are rare and account for only about 0.1% to 1.5% of all benign laryngeal tumors. 1,2 Among them, the incidence of laryngeal schwannoma is higher than that of laryngeal neurofibroma. 3 Schwannoma is rare benign nerve sheath tumor arising from Schwann cells and originates from the cranial, sympathetic, and peripheral nerves.…”

Section: Introductionmentioning

confidence: 99%

Paraglottic space schwannoma: a case report and literature review

Chen

Guo

et al. 2022

J Int Med Res

View full text Add to dashboard Cite

Neurogenic tumors located in the larynx are extremely rare. Among them, schwannoma is a benign encapsulated tumor originating from Schwann cells, which form nerve fiber sheaths in the peripheral nervous system. We herein report a case of a schwannoma arising from a rare subsite of the larynx and review the literature on laryngeal schwannoma. The case involved a woman with a 1-month history of globus pharyngeus and dysphagia without dysphonia. Rigid laryngoscopy and magnetic resonance imaging showed a large submucosal bulge toward the medial wall of the right pyriform fossa, pushing the right false and true vocal cords and aryepiglottic fold inward. A transcervical approach was used to completely excise the tumor without incisional biopsy or preliminary tracheotomy. Histology confirmed a benign schwannoma originating from the right paraglottic space, which was extremely rare. During follow-up, no evidence of recurrence or a residual mass was found. The transcervical approach is a useful and less invasive treatment for laryngeal schwannoma located in the paraglottic space.

show abstract

“…The gold standard in diagnosing schwannoma is HP analysis 5 . In our case histological diagnosis was based on Enger and Weiss' three histological criteria: 1) capsule presence, 2) presence of a stromal Antoni A (compacted, bipolar cells with nuclei arranged in palisade form) and/or Antoni B (loosely arranged spindle cells within a myxoid matrix) pattern and 3) positive S-100 staining 3 . However, it must be noted that incisional biopsy does not always result in correct diagnosis 4 .…”

Section: Discussionmentioning

confidence: 99%

Laryngeal schwannoma: A case report with short literature review

et al. 2021

View full text Add to dashboard Cite

Introduction. Laryngeal schwannomas are rare benign neurogenic tumors. They are usually localized in the supraglottic portion of the larynx.Case report. We report a rare case of laryngeal schwannoma with a focus on clinical presentation, diagnosis and management. A 61-year old male patient with a 3-year history of hoarseness underwent telescopic examination which revealed an oval submucosal tumefaction of the left ventricular fold extending over the left vocal fold toward the right ventricular fold. Multi-slice computed tomography showed a 22x15mm well defined, oval heterodense mass in the region of the left ventricular fold, extending toward the left vocal fold and the posterior commissure of the larynx, with signs of initial compression lesion of the thyroid cartilage. Biopsy and histopathology report revealed a primary benign encapsulated mesenchymal tumor, while immunohistochemistry analysis confirmed schwannoma diagnosis. The patient underwent tracheotomy and left hemilaryngectomy, with complete removal of the tumor. There were no signs of recurrence at the six-month follow-up. Conclusion.Schwannomas are rare among benign tumors of the larynx and might grow for years before being diagnosed. Biopsy with histopathology analysis is used to confirm the diagnosis of laryngeal schwannoma, although extreme care should be taken during biopsy.Treatment consists of complete surgical excision, while surgical approach depends on the size and localization of the tumor, as well as on the presence of a peduncle.

show abstract

Obstructive laryngeal schwannoma in a young female

Cited by 9 publications

References 11 publications

Diagnosis and Treatment of Laryngeal Schwannoma: A Systematic Review

Diagnosis and Treatment of Laryngeal Schwannoma: A Systematic Review

Paraglottic space schwannoma: a case report and literature review

Laryngeal schwannoma: A case report with short literature review

Contact Info

Product

Resources

About