Obstructive sleep apnea and asthma

Salles, Cristina; Terse-Ramos, Regina; Souza‐Machado, Adelmir; Cruz, Álvaro Augusto

doi:10.1590/s1806-37132013000500011

Cited by 34 publications

(29 citation statements)

References 68 publications

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“…Several publications have discussed the relationship between asthma and OSA. 59 60 61 62 63 Salles et al reported that OSA is prevalent in patients with asthma and is associated with disease severity. Asthma is associated with acute and chronic inflammation that affects the respiratory muscles, including upper airway dilators.…”

Section: Discussionmentioning

confidence: 99%

Comorbidities Associated with Obstructive Sleep Apnea: a Retrospective Study

Pinto

Ribeiro

Cavallini

et al. 2016

Int Arch Otorhinolaryngol

101

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Introduction Obstructive sleep apnea (OSA) is characterized by partial or complete recurrent upper airway obstruction during sleep. OSA brings many adverse consequences, such as hypertension, obesity, diabetes mellitus, cardiac and encephalic alterations, behavioral, among others, resulting in a significant source of public health care by generating a high financial and social impact. The importance of this assessment proves to be useful, because the incidence of patients with comorbidities associated with AOS has been increasing consistently and presents significant influence in natural disease history. Objective The objective of this study is to assess major comorbidities associated with obstructive sleep apnea (OSA) and prevalence in a group of patients diagnosed clinically and polysomnographically with OSA. Methods This is a retrospective study of 100 charts from patients previously diagnosed with OSA in our service between October 2010 and January 2013. Results We evaluated 100 patients with OSA (84 men and 16 women) with a mean age of 50.05 years (range 19–75 years). The prevalence of comorbidities were hypertension (39%), obesity (34%), depression (19%), gastroesophageal reflux disease (GERD) (18%), diabetes mellitus (15%), hypercholesterolemia (10%), asthma (4%), and no comorbidities (33%). Comorbidities occurred in 56.2% patients diagnosed with mild OSA, 67.6% with moderate OSA, and 70% of patients with severe OSA. Conclusion According to the current literature data and the values obtained in our paper, we can correlate through expressive values obesity with OSA and their apnea hypopnea index (AHI) values. However, despite significant prevalence of OSA with other comorbidities, our study could not render expressive significance values able to justify their correlations.

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Section: Discussionmentioning

confidence: 99%

Comorbidities Associated with Obstructive Sleep Apnea: a Retrospective Study

Pinto

Ribeiro

Cavallini

et al. 2016

Int Arch Otorhinolaryngol

101

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“…The correlation between OSAS and asthma was first investigated by Hudgel and Shrucard in the late 1970s (33). In asthmatic patients, OSAS contributes to poor asthma control (34) especially in patients who suffer most from nocturnal symptoms (35). It has been hypothesized that OSAS and asthma share most of their pathophysiological mechanisms; both often involve airways obstruction, gastroesophageal reflux, and obesity; moreover snoring could be a worsening factors for both the conditions.…”

Section: Sleep Disorders In Asthmamentioning

confidence: 99%

Sleep complaints and sleep breathing disorders in upper and lower obstructive lung diseases

Ferrando¹,

Bagnasco²,

Roustan³

et al. 2016

J. Thorac. Dis.

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Upper and lower obstructive lung diseases can induce sleep complaints and can be part of the pathogenesis of sleep breathing disorders. In fact, the physiological changes of the pattern of respiration during sleep, added to the airways disease can lead to symptomatic worsening of rhinitis, asthma and chronic obstructive pulmonary diseases (COPD); moreover, their functional and anatomical features can lead to sleep breathing disorders such as obstructive sleep apnea syndrome (OSAS). This review highlights the above-mentioned relationships and the effect of disease management on its comorbidities and the patient's quality of life. Rhinitis, asthma and COPD represent causes of sleep complaints that may be reduced with optimal management of these obstructive airways diseases. Continuous positive airway pressure (CPAP) treatment of sleep apnea needs to be tailored after optimization of the therapy of concomitant diseases, but it can often ameliorate comorbid disease.

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“…Several authors have reported a relationship between asthma and OSA [8][9][10][11][12][13][14]. The prevalence of OSA is higher among patients with adult asthma; OSA symptoms, which further deteriorate asthma symptoms, are commonly observed in the asthmatic population; thus, treating OSA can improve asthma symptoms [9][10][11][12].…”

Section: Introductionmentioning

confidence: 99%

“…The prevalence of OSA is higher among patients with adult asthma; OSA symptoms, which further deteriorate asthma symptoms, are commonly observed in the asthmatic population; thus, treating OSA can improve asthma symptoms [9][10][11][12]. Recent studies have shown that adult patients with asthma have a significantly higher risk of OSA [14,15].…”

Section: Introductionmentioning

confidence: 99%