Obstructive sleep apnea and electrocardiographic P‐wave morphology

Corotto, Paul S.; Kang, Hyojung; Massaro, Brianna; Harding, William C.; Shah, Neil; Gadi, Sneha; Bilchick, Kenneth C.; Mazimba, Sula; Kwon, Younghoon

doi:10.1111/anec.12639

Cited by 5 publications

(2 citation statements)

References 24 publications

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“…We first constructed a case cohort consisting of patients with prior history of AF and then constructed a control cohort of equal number by including consecutive patients without prior history of AF between June and December 2019. Only patients with a total sleep time (TST) >4 hours were included 16,17 …”

Section: Methodsmentioning

confidence: 99%

Atrial fibrillation is associated with central sleep apnea in clinic patients undergoing diagnostic polysomnography

Harmon

Stafford

Ibrahim

et al. 2020

Journal of Arrhythmia

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Introduction Sleep apnea is highly prevalent in patients with atrial fibrillation (AF). Obstructive sleep apnea (OSA) is the most common type, and best studied in the context of AF. However, recent investigations have indicated that central sleep apnea (CSA) may be a risk factor for incident AF. We evaluated the burden of CSA events in patients referred for diagnostic polysomnography (PSG) and whether AF is associated with CSA. Methods We identified patients with and without a history of AF who underwent clinically indicated PSG in a matched manner. OSA was defined as obstructive apnea‐hypopnea index (AHI) ≥15/h, and CSA was defined as central apnea index (CAI) ≥5/h. The association between AF and CSA was evaluated using multivariable logistic regression. Results Among 465 patients included, mean AHI was 25.5/h, and mean CAI was 1.7/h. OSA prevalence was 53.3%, while CSA prevalence was 8.4%. The prevalence of OSA in the AF and non‐AF groups (54.7% vs 52.0%, P = .56) was similar. CSA was more common in the AF group (12.3% vs 4.4%, P = .002). In multivariable analysis, AF (OR: 2.19 [1.02, 5.03], P = .05), male gender (OR: 2.5 [1.17, 5.84], P = .02), and older age (OR: 2.44, [1.16, 5.46], P = .02) were associated with CSA. Conclusion Though CSA is much less common than OSA in patients with AF, the presence of AF is independently associated with CSA.

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Section: Methodsmentioning

confidence: 99%

Atrial fibrillation is associated with central sleep apnea in clinic patients undergoing diagnostic polysomnography

Harmon

Stafford

Ibrahim

et al. 2020

Journal of Arrhythmia

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“…While awaiting results from several ongoing randomized controlled trials (RCTs) on this issue, screening and treatment of OSA in the presence of sleep-related symptoms seems reasonable [19] are warranted to identify high-risk groups for incident or recurrent AF among patients with OSA [20]. For example, it is possible that patients with OSA with either electrographic or structural left atrial pathology may be at much higher risk for developing AF [21][22][23]. Such information can help to arrive at treatment decisions in patients without obvious symptoms.…”

Section: Sleep Apnea and Atrial Fibrillationmentioning

confidence: 99%

Sleep Apnea and Heart

et al. 2019

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Scientific investigations in the past few decades have supported the important role of sleep in various domains of health. Sleep apnea is a highly prevalent yet underdiagnosed sleep disorder representing a valid cardiovascular risk factor, particularly for hypertension. While several studies have demonstrated the benefits of sleep apnea treatment on subclinical cardiovascular measures, there is a paucity of studies proving reduction of cardiovascular events and mortality. Sufficient and highquality sleep is also important in the maintenance of cardiovascular health. Future investigations should focus on improving identification of patients at greatest risk of adverse cardiovascular sequelae of sleep apnea and testing the therapeutic benefit of sleep apnea treatment in this vulnerable group.

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