2012
DOI: 10.4317/medoral.17706
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Obstructive sleep apnea syndrome (OSAS). Review of the literature

Abstract: Obstructive sleep apnea and hypopnea syndrome is characterized by repeated airway collapse during sleep. The li-terature describes multiple causes of the disease. The main cause is a reduction of the expansion forces of the pharyngeal dilator muscles, as in situations of genioglossal muscle dysfunction, and discoordination between the inspiratory activity of the muscle and respiratory effort, which play an important role in progression of the disease. Other described causes are soft tissue disorders, such as m… Show more

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Cited by 124 publications
(107 citation statements)
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“…Patients with OSA can be defined as having daytime sleepiness, which may be associated with hypertension, nocturnal hypoxemia, cerebrovascular pathology, and cardiac problems, especially arrhythmia (3). The pathophysiological factors associated with OSA are very complex, ranging from those pertaining to ventilatory control or sensory function to anatomical abnormalities that may promote upper airway collapse, including skeletal, soft tissue and pharyngeal muscle factors (4,5). One specific anatomical location seems unlikely to be a major cause of upper airway collapse, and it is more probably a dynamic phenomenon involving several factors and locations (5,6).…”
Section: Introductionmentioning
confidence: 99%
“…Patients with OSA can be defined as having daytime sleepiness, which may be associated with hypertension, nocturnal hypoxemia, cerebrovascular pathology, and cardiac problems, especially arrhythmia (3). The pathophysiological factors associated with OSA are very complex, ranging from those pertaining to ventilatory control or sensory function to anatomical abnormalities that may promote upper airway collapse, including skeletal, soft tissue and pharyngeal muscle factors (4,5). One specific anatomical location seems unlikely to be a major cause of upper airway collapse, and it is more probably a dynamic phenomenon involving several factors and locations (5,6).…”
Section: Introductionmentioning
confidence: 99%
“…Obstructive sleep apnea syndrome is observed more commonly in middle-aged individuals and its prevalence among adults is estimated to be about 2-4% (9). No published study showing the prevalence of OSAS through PSG is available in our country.…”
Section: Discussionmentioning
confidence: 97%
“…Asian subjects are known to have mandibulo -maxillary protrusion. Mandibular disparities have been established as a known cause of Obstructive sleep apnea syndrome [18] .…”
Section: Discussionmentioning
confidence: 99%