“…Physicians have not long recognized many adverse effects, including OIC, with long‐term opioid administration , and patients may resist discussing their bowel habits with healthcare providers. However, it is important to facilitate such discussion, because a number of complications and adverse effects can occur with OIC, including dyspepsia, reflux, bloating, spasm, cramping , fecal impaction , urinary obstruction or infection , pain, hospitalizations, lessened quality of life, and interference with the pain treatment regimen .…”