Obturator Manufacturing for Oronasal Fistula after Cleft Palate Repair: A Review from Handicraft to the Application of Digital Techniques

Chen, Jiali; Yang, Renjie; Shi, Bing; Xu, Yaqing; Huang, Hayden

doi:10.3390/jfb13040251

Cited by 6 publications

(8 citation statements)

References 119 publications

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“…chirurgicznego oraz implantologicznego, do wytwarzania indywidualnych elementów zespalających odłamy kostne, szablonów do implantacji czy uzupełnień protetycznych. 1,4,9,21,28 Kortes i wsp. przedstawili opis przypadku cyfrowego wytwarzania natychmiastowej płytki pooperacyjnej z obturatorem zamkniętym pustym w technologii druku 3 D, wykorzystując dane ze skanów rezonansu magnetycznego (MRI) i tomografii komputerowej (CT), wykonanych przed zabiegiem resekcji.…”

Section: Wykorzystanie Technologii Cyfrowych W Rehabilitacji Protetyc...unclassified

Application of digital technologies to prosthetic rehabilitation of patients after surgical treatment of head and neck neoplasms.

Cybulska¹,

Szerszeń²

2023

Prosthodontics

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Surgical resection is the primary treatment modality for patients with head and neck neoplasms. Tissue defects resulting from the procedure cause disturbances in function and aesthetics. In addition, numerous changes in the stomatognathic system may occur in this group of patients, making prosthetic rehabilitation difficult. Methods to simplify production technology and to increase the precision of prosthetic replacements are constantly sought. Dynamically developing CAD/CAM technologies are also more and more frequently used in the treatment of postoperative patients. The use of computer-aided design and manufacturing enables the creation of precise restorations, shortens the rehabilitation time, facilitates archiving of data and improves communication between different departments. The ability to obtain data from magnetic resonance images (MRI), computed tomography (CT), 3D photogrammetry and intra-oral scanning (IS) enables accurate planning of resection procedures and designing prosthetic restorations; patients can use them immediately following the surgery to restore function, aesthetics and comfort of life. The development of CAD/CAM techniques and

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Section: Wykorzystanie Technologii Cyfrowych W Rehabilitacji Protetyc...unclassified

Application of digital technologies to prosthetic rehabilitation of patients after surgical treatment of head and neck neoplasms.

Cybulska¹,

Szerszeń²

2023

Prosthodontics

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“…This can lead to a cascade of complications including compromised speech, dysphagia, nasal regurgitation, and impaired maxillofacial growth. The rate of postoperative palatoplasty failure ranges from 2.4% to 55%, related to the cleft width, Veau type, and surgical repair method [4–7,8 ▪ ]. Recurrent palatal defects can be extremely challenging to manage due to factors such as scarring and local tissue hypovascularity, leading to flap loss and wound dehiscence.…”

Section: Introductionmentioning

confidence: 99%

Managing massive palatial defect secondary to palatoplasty failures: an in-depth analysis

Boot,

Winters

2024

Current Opinion in Otolaryngology &Amp; Head &Amp; Neck Surgery

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Purpose of review Massive palatal defects resulting from palatoplasty failures arising from cleft palate repair complications present ongoing challenges in clinical practice. The purpose of this review is to provide up-to-date insights into aetiology, risk factors, surgical techniques, and adjunctive therapies, aiming to enhance the understanding of such complex cases, and optimize patient outcomes. Recent findings Primary palatoplasty has fistula recurrence rates ranging from 2.4% to 55%. Factors such as cleft width, surgical repair method, and patient characteristics, influence the likelihood of failure. Classifications such as the Pakistan Comprehensive Classification and Richardson's criteria aid in assessing defects. Surgical options range from local flaps and revision palatoplasty to regional flaps (e.g., buccinator myomucosal, facial artery-based flaps, tongue flaps, nasal septal flaps) to free microvascular flaps. Alternative approaches include obturator prostheses, and acellular dermal matrix has been used as an adjuvant to multiple repair techniques. Hyperbaric oxygen therapy has emerged as an adjunctive therapy to enhance tissue healing. Summary This comprehensive review underscores the intricate challenges associated with massive palatal defects resulting from palatoplasty failures. The diverse range of surgical and nonsurgical options emphasizes the importance of patient-centric, individualized approaches. Practitioners, armed with evidence-based insights, can navigate these complexities, offering tailored interventions for improved patient outcomes.

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“…Excellent biocompatibility is a prerequisite for biomedical implant materials. Unlike Ti and its alloys, whose biocompatibility has been established for medical use [10,11], the toxicity of Zn and its alloys remains a subject of debate. Considering the 3Rs principles in animal research, i.e., to reduce, refine, or replace the use of animals in biomedical research, the in vitro assessment is indispensable in estimating the biocompatibility of the novel Zn-based BMs [12,13].…”

Section: Introductionmentioning

confidence: 99%

Cytotoxicity of Biodegradable Zinc and Its Alloys: A Systematic Review

Liu

et al. 2023

JFB

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Zinc-based biodegradable metals (BMs) have been developed for biomedical implant materials. However, the cytotoxicity of Zn and its alloys has caused controversy. This work aims to investigate whether Zn and its alloys possess cytotoxic effects and the corresponding influence factors. According to the guidelines of the PRISMA statement, an electronic combined hand search was conducted to retrieve articles published in PubMed, Web of Science, and Scopus (2013.1–2023.2) following the PICOS strategy. Eighty-six eligible articles were included. The quality of the included toxicity studies was assessed utilizing the ToxRTool. Among the included articles, extract tests were performed in 83 studies, and direct contact tests were conducted in 18 studies. According to the results of this review, the cytotoxicity of Zn-based BMs is mainly determined by three factors, namely, Zn-based materials, tested cells, and test system. Notably, Zn and its alloys did not exhibit cytotoxic effects under certain test conditions, but significant heterogeneity existed in the implementation of the cytotoxicity evaluation. Furthermore, there is currently a relatively lower quality of current cytotoxicity evaluation in Zn-based BMs owing to the adoption of nonuniform standards. Establishing a standardized in vitro toxicity assessment system for Zn-based BMs is required for future investigations.

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Obturator Manufacturing for Oronasal Fistula after Cleft Palate Repair: A Review from Handicraft to the Application of Digital Techniques

Cited by 6 publications

References 119 publications

Application of digital technologies to prosthetic rehabilitation of patients after surgical treatment of head and neck neoplasms.

Application of digital technologies to prosthetic rehabilitation of patients after surgical treatment of head and neck neoplasms.

Managing massive palatial defect secondary to palatoplasty failures: an in-depth analysis

Cytotoxicity of Biodegradable Zinc and Its Alloys: A Systematic Review

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