OC16.04: Intrauterine open fetal surgery for correction of isolated occipital encephalocele

Milani, Hérbene José Figuinha; Barbosa, M. P.; Sarmento, Stéphanno Gomes Pereira; Cavalheiro, Sérgio; Suriano, Ítalo Capraro; Moron, A.

doi:10.1002/uog.17655

Cited by 1 publication

(2 citation statements)

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“…[5,8] Gadgil et al documented in their cohort that progressive herniation is defined as an increment of >5% in the absolute value of neural tissue within the encephalocele. [5,9] An additional investigation is necessary, including the use of a larger database and studies in animals to demonstrate the progressive hernia of functional neural tissue, which later presents damage within the uterine cavity, as well as the role it plays in the pathophysiology of an occipital encephalocele.…”

Section: Discussionmentioning

confidence: 99%

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Fetal surgery for occipital encephalocele: A case report

Méndez,

Mena,

Aguilar

et al. 2023

Surgical Neurology International

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Background: Occipital encephalocele is a congenital defect of the neural tube at the level of the cranial midline, which results in herniation of meninges and brain tissue. The results of the management of myelomeningocele study determine the maternal and fetal risks for an open fetal surgery and have motivated the constant review of the concepts and strategies which the pediatric neurosurgeon can employ for the treatment of neural tube defects in the prenatal period. Case Description: We present a case of a female patient in utero of 26 gestational weeks with the diagnosis of an occipital encephalocele treated by open fetal surgery. During week 20 of gestation, the diagnosis of occipital encephalocele was made by ultrasound, which was corroborated by fetal magnetic resonance that showed cranial protrusion of neural and meningeal content in the occipital region, measuring 1.6 × 2.8 × 3.3 cm with an approximate volume of 7.7 cc through a bone defect of 6 mm. The closure of the defect was performed by the postnatal surgical technique adapted to the open fetal surgery. Later, the patient was born transabdominal with a 2.8 cm occipital wound, with suture points and approximated borders, normocephalic, without clinical signs of sepsis, hydrocephalus, or overt neurologic compromise. Conclusion: Open fetal surgery is a therapeutic option in the face of an isolated occipital encephalocele. This case report demonstrates the viability of the surgical procedure by the adaptation of a postnatal surgical technique to a prenatal surgery. Further studies are needed to evaluate the long-term functional results, comparing them with those seen in patients who undergo a postnatal procedure.

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Section: Discussionmentioning

confidence: 99%

“…documented in their cohort that progressive herniation is defined as an increment of >5% in the absolute value of neural tissue within the encephalocele. [ 5 , 9 ]…”

Section: Discussionmentioning

confidence: 99%