Occipital epilepsies: identification of specific and newly recognized syndromes

Taylor, I

doi:10.1093/brain/awg080

Cited by 158 publications

(130 citation statements)

References 137 publications

Supporting

Mentioning

117

Contrasting

Unclassified

Order By: Relevance

“…Moreover they were very frequently marked as bursts and were diffuse. This could be related to the fact that the classical interictal pattern of the idiopathic, and more rarely cryptogenic, occipital epilepsies, comprises runs of nearly continuous high amplitude, rhythmic 2-3 Hz, unilateral or bilateral posterior sharp and slow wave complexes (Taylor et al 2003). It could therefore be argued that posterior quadrant IEDs are more frequently diffuse, have long duration, and correlate with the presence of deactivation only because they had slow waves.…”

Section: Discussionmentioning

confidence: 99%

Negative BOLD Response to Interictal Epileptic Discharges in Focal Epilepsy

et al. 2013

View full text Add to dashboard Cite

In EEG-fMRI studies, BOLD responses related to interictal epileptic discharges (IEDs) are most often the expected positive response (activation) but sometimes a surprising negative response (deactivation). The significance of deactivation in the region of IED generation is uncertain. The aim of this study was to determine if BOLD deactivation was caused by specific IED characteristics. Among focal epilepsy patients who underwent 3T EEG-fMRI from 2006 to 2011, those with negative BOLD having a maximum t-value in the IED generating region were selected.As controls, subjects with maximum activation in the IED generating region were selected. We established the relationship between the type of response (activation/deactivation) and (1) presence of slow wave in the IEDs, (2) lobe of epileptic focus, (3) occurrence as isolated events or bursts, (4) spatial extent of the EEG discharge. Fifteen patients with deactivation and 15 with activation were included. The IEDs were accompanied by a slow wave in 87 % of patients whose primary BOLD was a deactivation and only in 33 % of patients with activation. In the deactivation group, the epileptic focus was more frequently in the posterior quadrant and involved larger cortical areas, whereas in the activation group it was more frequently temporal. IEDs were more frequently of long duration in the deactivation group. The main factor responsible for focal deactivations is the Correspondence to: Jean Gotman. Electronic supplementary material The online version of this article

show abstract

Section: Discussionmentioning

confidence: 99%

Negative BOLD Response to Interictal Epileptic Discharges in Focal Epilepsy

et al. 2013

View full text Add to dashboard Cite

show abstract

“…28 FS dogs may experience focal idiopathic epilepsy originating from occipital or other posterior areas.…”

Section: Discussionmentioning

confidence: 99%

Electroencephalography Findings in Healthy and Finnish Spitz Dogs with Epilepsy: Visual and Background Quantitative Analysis

et al. 2007

View full text Add to dashboard Cite

Background: Qualitative and quantitative electroencephalography (EEG) parameters of healthy and Finnish Spitz dogs with epilepsy have not been determined.Objective: To determine if EEG can provide specific characteristics to distinguish between healthy dogs and dogs with epilepsy.Animals: Sixteen healthy and 15 Finnish Spitz dogs with epilepsy. Methods: A prospective clinical EEG study performed under medetomidine sedation. Blinded visual and quantitative EEG analyses were performed and results were compared between study groups.Results: Benign epileptiform transients of sleep and sleep spindles were a frequent finding in a majority of animals from both groups. The EEG analysis detected epileptiform activity in 3 Finnish Spitz dogs with epilepsy and in 1 healthy Finnish Spitz dog. Epileptiform activity was characterized by spikes, polyspikes, and spike slow wave complexes in posterior-occipital derivation in dogs with epilepsy and with midline spikes in control dog. The healthy dogs showed significantly less theta and beta activity than did the dogs with epilepsy (P , .01), but the only significant difference between healthy dogs and dogs with untreated epilepsy was in the alpha band (P , .001). Phenobarbital treatment increased alpha, beta (P , .001), and theta (P , .01), and decreased delta (P , .001) frequency bands compared with dogs with untreated epilepsy.Conclusions and Clinical Importance: Benign epileptiform transients of sleep could be easily misinterpreted as epileptiform activity. Epileptiform activity in Finnish Spitz dogs with epilepsy seems to originate from a posterior-occipital location. The EEG of dogs with epilepsy exhibited a significant difference in background frequency bands compared with the control dogs. Phenobarbital treatment markedly influenced all background activity bands. Quantitative EEG analysis, in addition to visual analysis, seems to be a useful tool in the examination of patients with epilepsy.

show abstract

“…Visual symptomatology is predominated by elementary, rarely complex visual hallucinations, illusions, palinopsia and amaurosis. Visual hallucinations often appear in the form of small colorful circles that move within the visual field or are rarely shining and of twinkling pulsating lights (2). Elementary visual hallucinations are often followed by oculomotor symptoms with a contralateral tonic deviation of the eyes and head, and epileptic nistagmus with pulsating movements.…”

Section: Introductionmentioning

confidence: 99%

Occipital lobe epilepsy or migraine headache

Skrijelj

Mulić

2016

SANAMED

View full text Add to dashboard Cite

Introduction: Occipital lobe epilepsies are rarely met in clinical practice, but when they occur, they can be misdiagnosed as migraine-like headache. Their prevalence ranges from 5% to 10% of all epilepsies. Seizures can occur at any age; etiologically speaking they can be symptomatic, cryptogenic and idiopathic (most often onsetis in childhood). Clinical symptomatology is manifested by partial epileptic seizures in the sense of visual elementary and/or complex manifestations, palinopsia, amaurosis, tonic head deviation, bulbus, nistagmus and headache. Propagation discharge to neighbour areas (temporal, parietal and frontal) is a frequent occurrence appearing with complex partial seizures frequently finishing with secondary generalized tonic-clonic (GTC) seizures. Case report: We are presenting a17-year-old male patient who has suffered from attacks of visual problems with headache since 10 years of age. All the time it is treated as a migraine headache. During the last attack of headache the patient also had a loss of consciousness, EEG that was performed for the first time evidenced epileptic discharges of the occipital area.The therapy also included treatment with antiepileptic drug pregabalin resulting in seizure withdrawal. Conclusion:The appearance of visual symptoms followed by headache is most frequently qualified as migraine triggered headache. However, when antimigraine therapy does not give favorable results epileptic headache should be suspected, with obligatory performance of EEG recording. Occipital lobe epilepsy often presents diagnostic dilemmas due to clinical manifestations that are similar to that of non-migraine headache.

show abstract

Occipital epilepsies: identification of specific and newly recognized syndromes

Cited by 158 publications

References 137 publications

Negative BOLD Response to Interictal Epileptic Discharges in Focal Epilepsy

Negative BOLD Response to Interictal Epileptic Discharges in Focal Epilepsy

Electroencephalography Findings in Healthy and Finnish Spitz Dogs with Epilepsy: Visual and Background Quantitative Analysis

Occipital lobe epilepsy or migraine headache

Contact Info

Product

Resources

About