Occult Contralateral Carcinoma in Patients with Unilateral Papillary Thyroid Microcarcinoma

Abstract

Based on our findings, total thyroidectomy, including the contralateral lobe, should be considered for the treatment of unilateral PTMC if it presents as a multifocal tumor in the unilateral lobe and/or if nodules are found in the contralateral lobe during preoperative evaluation.

Predictive Factors for Incidental Contralateral Carcinoma in Patients with Unilateral Micropapillary Thyroid Carcinoma

“…Some previous studies reported similar findings to our study that ipsilateral multifocal disease was the predictive factor for contralateral cancer in PTMC [16]. But the relation between multifocality and LN metastasis or recurrence is controversial.…”

“…For PTMC, up to 40% of patients have been reported to have contralateral carcinoma at the time of histological review, but these incidence show a considerable difference according to study population [14,15]. In our results, 19.6% of PTMC had contralateral carcinoma and this incidence is consistent with previous study restricted to those with preoperatively unilateral confined PTMC [16].…”

Cervical Lymph Node Dissection in Papillary Thyroid Cancer: Pattern and Predictive Factors of Regional Lymph Node Metastas

“…Neck metastases were found in 51/101 (50.5%) participants, in 19 (37.3%) ofwhom the lateral compartment was also affected, agreeing with other authors' reports. No participant exhibited metastases contralateral to the primary tumor, which is also asomewhat rare finding in other studies (9.8-18.9%) [8][9][10]. The patients with neck metastasis had more dissected lymph nodes than theones without metastasis (p = 0.01), but the lymph node size did not differ betweengroups (p = 0.34).…”

Frequency of High-Risk Characteristics Requiring Total Thyroidectomy for 1–4 cm Well-Differentiated Thyroid Cancer

“…In the absence of a clear consensus, the decision on the extent of thyroidectomy and the role of RAI is always one that should be made between the patient, surgeon, and endocrinologist, as reflected in the present results. About 30% of patients with low-risk WDTC harbor contralateral cancers (12,13). While the clinical relevance of these cancers is still unclear, these tumors may represent multicentricity or intrathyroidal spread (14,15).…”