2024
DOI: 10.1097/rlu.0000000000005191
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Occult SMARCA4-Deficient Undifferentiated Carcinoma Unmasked by 68Ga-FAPI-46 PET/CT

Weizhi Xu,
Long Zhao,
Jiayu Cai
et al.

Abstract: SMARCA4-deficient undifferentiated tumors (SMARCA4-dUT) are rare and aggressive neoplasms commonly found in male smokers and portend a poor prognosis. In this case, we reported 18F-FDG and 68Ga-FAPI-46 PET/CT findings in an occult SMARCA4-dUT located in the left pulmonary hilum along with mediastinal lymph node metastases. 68Ga-FAPI-46 PET/CT showed superiority over 18F-FDG for detecting SMARCA4-dUT lesions. This case highlighted that 68Ga-FAPI-46 PET/CT may be a promising imaging modality in the evaluation of… Show more

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