Occupational Allergic Disease in Cereal Workers by Stored Grain Pests

Armentia, Alicia; Martínez, Javier Jesús González; Castrodeza, R; Martı́nez, Jorge; Jimeno, Amor López; Mendez, Javier A.; Stolle, R.

doi:10.3109/02770909709055378

Cited by 48 publications

(16 citation statements)

References 32 publications

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“…Armentia et al [66] evaluated the prevalence of sensitization to different mite species in grain workers and detected a prevalence of 38% for L. destructor and Tyrophagus putrescentiae, of 34% for B. kulagini, and of 24% for Acarus siro and Chortoglyphus arcuatus. A study conducted in Galicia in 469 adult patients residing in rural and urban areas demonstrated a rate of sensitization of 34.4% for L. destructor and/or T. putrescentiae [67].…”

Section: Clinical Significance Of Sensitization To Domestic Mitesmentioning

confidence: 99%

Mite allergens

Fernández-Caldas¹,

Calvo²

2005

Curr Allergy Asthma Rep

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There is an increasing awareness of the health implications of mite sensitivity, as it is closely related to asthma. Mite allergy constitutes a complex worldwide problem, with sanitary and economical implications. Not only are mite species present in house dust, producing potent allergens, but other, less studied species are also responsible for significant allergic reactions in occupational settings. In this review, we focus on the growing number of mite species that are implicated in allergic cutaneous and respiratory diseases in humans. Mite allergy is not restricted only to the human "indoor" environment, because numerous reports clearly demonstrate that many species that can induce sensitization and symptoms are encountered in occupational settings. An important component of allergy research is the evaluation of the allergenic cross-reactivity to verify to what extent different mite species have unique, species-specific, or cross-reactive allergens. The results of these investigations have important clinical consequences for the diagnosis and treatment of allergic diseases. Internationally standardized mite extracts are needed to compare sensitization rates around the world and clearly establish risk factors associated with sensitization and asthma. In spite of recent controversial results, a significant reduction in the exposure to mite allergens continues to be an important challenge and one of the main goals in the treatment of mite-induced respiratory symptoms. In many cases, this reduction must be achieved in the workplace as well as in the home environment.

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Section: Clinical Significance Of Sensitization To Domestic Mitesmentioning

confidence: 99%

Mite allergens

Fernández-Caldas¹,

Calvo²

2005

Curr Allergy Asthma Rep

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“…In particular, the significance of insects as occupational allergens is well established [1,6,7]. Considering that a large percentage of the general allergic asthma population is sensitized to any insect allergen, insect allergens are also presumed as important environmental allergens [8,9,10,11,12,13].…”

Section: Introductionmentioning

confidence: 99%

Allergenicity and Cross-Reactivity of Booklice <i>(Liposcelis bostrichophila)</i>: A Common Household Insect Pest in Japan

Fukutomi¹,

Kawakami²,

Taniguchi³

et al. 2011

Int Arch Allergy Immunol

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Background: Booklice (Liposcelis bostrichophila) are a common household insect pest distributed worldwide. Particularly in Japan, they infest ‘tatami’ mats and are the most frequently detected insect among all detectable insects, present at a frequency of about 90% in dust samples. Although it has been hypothesized that they are an important indoor allergen, studies on their allergenicity have been limited. Methods: To clarify the allergenicity of booklice and the cross-reactivity of this insect allergen with allergens of other insects, patients sensitized to booklice were identified from 185 Japanese adults with allergic asthma using skin tests and IgE-ELISA. IgE-inhibition analysis, immunoblotting and immunoblotting-inhibition analysis were performed using sera from these patients. Allergenic proteins contributing to specific sensitization to booklice were identified by two-dimensional electrophoresis and two-dimensional immunoblotting. Results: The booklouse-specific IgE antibody was detected in sera from 41 patients (22% of studied patients). IgE inhibition analysis revealed that IgE reactivity to the booklouse allergen in the sera from one third of booklouse-sensitized patients was not inhibited by preincubation with extracts from any other environmental insects in this study. Immunoblotting identified a 26-kD protein from booklouse extract as the allergenic protein contributing to specific sensitization to booklice. The amino acid sequence of peptide fragments of this protein showed no homology to those of previously described allergenic proteins, indicating that this protein is a new allergen. Conclusions: Sensitization to booklice was relatively common and specific sensitization to this insect not related to insect panallergy was indicated in this population.

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“…It is known that sensitization to allergens derived from storage mites may lead to occupational allergic disorders (2,3). There has been increasing interest in the allergenicity of storage mites in recent years (13).…”

mentioning

confidence: 99%

Immunoglobulin E Binding Reactivity of a Recombinant Allergen Homologous to α-Tubulin from Tyrophagus putrescentiae

Jeong

Lee

et al. 2005

Clin Vaccine Immunol

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Storage mites may cause allergic respiratory diseases in urban areas as well as pose an occupational hazard in rural areas. Characterization of storage mite allergens is important for the development of diagnostic and therapeutic agents against mite-associated allergic disorders. Here we report on the cloning and expression of ␣-tubulin from the storage mite (Tyrophagus putrescentiae). The deduced amino acid sequence of the ␣-tubulin from the storage mite showed as much as 97.3% identity to the ␣-tubulin sequences from other organisms. The highly conserved amino acid sequences of ␣-tubulins across different species of mites may indicate that cross-reactivity for this potential allergen exists. The frequency of immunoglobulin E reactivity of this recombinant protein is 29.3% in sera from storage mite-allergic subjects.

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Occupational Allergic Disease in Cereal Workers by Stored Grain Pests

Cited by 48 publications

References 32 publications

Mite allergens

Mite allergens

Allergenicity and Cross-Reactivity of Booklice <i>(Liposcelis bostrichophila)</i>: A Common Household Insect Pest in Japan

Immunoglobulin E Binding Reactivity of a Recombinant Allergen Homologous to α-Tubulin from Tyrophagus putrescentiae

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