Occupational allergies caused by latex

Ahmed, Debra D. F.; Sobczak, Steven C; Yunginger, John W.

doi:10.1016/s0889-8561(02)00079-6

Cited by 44 publications

(4 citation statements)

References 79 publications

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“…No final do século XVIII o látex começou a ser utilizado nos países industrializados para impermeabilizar o vestuário. No entanto, só com a descoberta do processo da vulcanização (união dos polímeros de hidrocarbonetos da borracha por pontes sulfito), por Charles Goodyear e depois, com o início da produção de pneus por John Dunlop, é que o látex entrou verdadeiramente na sua era industrial (5) (6) (7) (8). O primeiro relato de alergia ao látex surgiu em 1979 (9).…”

Section: Noção Históricaunclassified

“…Os primeiros casos de reações anafiláticas intraoperatórias ao látex foram descritos na Europa em 1984 (10). Outros relatos de anafilaxia foram feitos, não só intraoperatória, mas também durante os atos médicos, como na colocação de cateteres (8), procedimentos ginecológicos (11) e tratamentos dentários (7). Foram também descritos casos de anafilaxia após exposição a preservativos, balões, brinquedos de borracha, materiais com revestimento de látex e vários outros objetos contendo borracha (5) (6) (7) (8) (12).…”

Section: Noção Históricaunclassified

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Alergia ao Látex em Contexto Ocupacional

Vale,

Rocha,

Matos

et al. 2023

RPSO

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Introduction/framework/objectives Latex allergy is recognized as a widespread health problem that assumed serious proportions in the 1990s. Although preventive measures have markedly decreased its incidence, recent studies have shown that it remains an important health problem in certain population groups, particularly in developing countries. This work aims to provide a comprehensive review of the current status of occupational latex allergies. We summarize various aspects of this condition, such as prevalence, risk groups, latex allergens, the diagnostic approach, prevention, and treatment. Methodology A bibliographic review was carried out in January 2023 in the following databases: PubMed/Medline, Cochrane Library, Evidence-based Medicine, Canadian Medical Association, Practice Guidelines and National Guideline Clearinghouse. Content Repeated exposure to latex in an occupational context can lead to worker sensitivity, with a significant clinical and socio-economic impact. We summarize various aspects of this condition, such as prevalence, risk groups, latex allergens, the diagnostic approach, prevention and treatment. Discussion and Conclusions The history of latex allergies has demonstrated that potent allergens such as Natural Rubber Latex proteins can cause rapid immunoglobulin-E-mediated sensitization and clinical allergies, reaching serious proportions in highly exposed individuals. Occupational exposure has a decisive influence on the allergen sensitivity profile, with important clinical and therapeutic consequences. The effectiveness of secondary prevention measures is limited. Thus, it is essential to implement early primary prevention measures in individuals belonging to risk groups, to avoid or minimize exposure to latex allergens. KEYWORDS: Healthcare Professionals, Latex allergy, Latex gloves, Latex hypersensitivity, Natural rubber latex, Occupational diseases, Occupational health, Occupational Medicine.

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Section: Noção Históricaunclassified

Alergia ao Látex em Contexto Ocupacional

Vale,

Rocha,

Matos

et al. 2023

RPSO

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“…The in vitro determination of specific IgE antibodies to whole latex is not always associated with clinically relevant protein sensitivity. A correct diagnosis is therefore dependent on the use of well-characterised purified allergens and, where appropriate, investigation of the allergenic material in question [6,7,8,9,10]. Once sensitised to latex, patients may experience symptoms such as itchy eyes, runny nose, sneezing, wheezing, coughing, asthma, itchy skin and urticaria and even anaphylaxis [11, 12].…”

Section: Introductionmentioning

confidence: 99%

Occupational Allergy to Latex among Loom Tuners in a Textile Factory

Lopata

Adams²,

Kirstein³

et al. 2007

Int Arch Allergy Immunol

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Background: Occupational allergy to latex is generally reported from occupational groups such as health care workers; however, few reports derive from other occupational settings. Methods: Two male subjects working as loom tuners in a textile manufacturing plant developed severe allergic reactions during the cutting and weaving of elastic bands, initially not suspected to contain latex constituents. Clinical evaluation and lung function tests were supplemented by skin prick testing, specific IgE evaluation and basophil activation assays with extracted elastic bands. Results: Both workers presented with rhinitis, episodes of tight chest and itchy eyes. Initial spirometry was normal with no significant reversibility; however, a histamine challenge test was positive in one worker. Skin prick testing to a battery of common inhalant allergens was negative; however, raised IgE levels were detected to latex using ImmunoCAP. On further testing, the specific IgE response was directed mainly to the major latex allergens rHev b 5, rHev b 6.01, rHev b 6.02 and nHev b 13. Basophils of the two workers, but not the unaffected control subjects, were strongly activated by extracts of the elastic and the cutting dust material. Conclusions: Workers are at high risk of becoming sensitised to latex allergens when exposed to excessive dust produced by loom tuning machines. Latex sensitisation should therefore be considered in workers developing unexplained work-related allergic reactions (including asthma) associated with unlabelled materials in the textile industry.

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“…Atopy is a hypersensitivity state or allergy with a hereditary predisposition. Atopic individuals have a genetic predisposition to make IgE antibodies in response to an allergen exposure (Anand & Routes, 2004) and are prone to IgE-mediated allergic reactions (i.e., they are more easily sensitized to allergens) (Felt-Ahmed, Sobczak, & Yunginger, 2003) . They may have a personal or family history of eczema, asthma, or seasonal allergic rhinitis.…”

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confidence: 99%

Thiuram Allergy—A Potential Dermal Allergy among Health Care Workers

Green-McKenzie¹,

Pak²,

Crawford³

et al. 2009

AAOHN Journal

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Occupational health nurses should be cognizant of the myriad exposures that can result in dermal reactions among health care workers. M yriad exposures can result in dermal reactions among health care workers. An interesting case occurred at an occupational and environmental medicine clinic when a 39-year-old surgeon presented to the clinic with a chief complaint of a raised, pruritic, and erythematous rash involving her face, neck, and upper extremities. The rash, located on the exposed skin of her neck and chest in a V-shaped pattern, occurred shortly after entering the operating room and resolved within 48 hours. After resolution, the skin around her eyes would desquamate. The rash had been worsening during the previous few months. Her symptoms seemed to worsen after each exposure, improving when she was away from the operating room during weekends and holidays. The surgeon also reported washing her hands more than 20 times each day.

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Occupational allergies caused by latex

Cited by 44 publications

References 79 publications

Alergia ao Látex em Contexto Ocupacional

Alergia ao Látex em Contexto Ocupacional

Occupational Allergy to Latex among Loom Tuners in a Textile Factory

Thiuram Allergy—A Potential Dermal Allergy among Health Care Workers

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