Occupational asthma

Quirce, Santiago; Sastre, Joaquı́n

doi:10.1097/mcp.0000000000000535

Cited by 17 publications

(6 citation statements)

References 36 publications

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“…Unfortunately, for occupational allergens these are not commonly available. 25 The need for standardization is further highlighted since the alternative, a specific allergen inhalation challenge test, is not generally feasible for seafood processing workers.…”

Section: Discussionmentioning

confidence: 99%

Exposures and Health Effects of Bioaerosols in Seafood Processing Workers - a Position Statement

Bønløkke

Bang

Aasmoe

et al. 2019

Journal of Agromedicine

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Occupational hazards exist in the processing of seafood both in land-based facilities as well as on board vessels. Recent findings on occupational injury and respiratory health risks among seafood processing workers were presented and discussed at the IFISH5 conference. Particular emphasis was put on the challenges that im/migrant workers encounter, the greater risks onboard factory vessels, especially where processing machinery are retrofitted to older vessels not primarily designed for this purpose, and the difficulties in assessing and preventing bioaerosol exposures and associated respiratory health risks despite recent advances in characterising agents responsible for allergic and non-allergic reactions. Based on appraisal of existing knowledge in the published literature and new findings presented at the conference, recommendations for immediate actions as well as for future research have been proposed. Among these include the importance of improving extraction ventilation systems, optimising machinery performance, enclosure of bioaerosol sources, improved work organization, and making special efforts to identify and support the needs of im/migrant workers to ensure they also benefit from such improvements. There is a need for studies that incorporate longitudinal study designs, have improved exposure and diagnostic methods, and that address seafood processing in countries with high seafood processing activities such as Asia and those that involve im/migrant workers worldwide. The medical and scientific community has an important role to play in prevention but cannot do this in isolation and should cooperate closely with hygienists, engineers, and national and international agencies to obtain better health outcomes for workers in the seafood industry.

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Section: Discussionmentioning

confidence: 99%

Exposures and Health Effects of Bioaerosols in Seafood Processing Workers - a Position Statement

Bønløkke

Bang

Aasmoe

et al. 2019

Journal of Agromedicine

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“…Biomarkers could increase the likelihood for a diagnosis of OA. According to a recent review the most accurate biomarkers for diagnosis and follow up are those associated with type 2 airway inflammation-sputum eosinophilia and FeNO [90].…”

Section: Biomarkers For the Assessment Of Airway Inflammationmentioning

confidence: 99%

Progress in Occupational Asthma

Tiotiu

Novakova²,

Labor

et al. 2020

IJERPH

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Occupational asthma (OA) represents one of the major public health problems due to its high prevalence, important social and economic burden. The aim of this review is to summarize current data about clinical phenotypes, biomarkers, diagnosis and management of OA, a subtype of work-related asthma. Most studies have identified two phenotypes of OA. One is sensitizer-induced asthma, occuring after a latency period and caused by hypersensitivity to high- or low-molecular weight agents. The other is irritant-induced asthma, which can occur after one or more exposures to high concentrations of irritants without latency period. More than 400 agents causing OA have been identified and its list is growing fast. The best diagnostic approach for OA is a combination of clinical history and objective tests. An important tool is a specific inhalation challenge. Additional tests include assessments of bronchial hyperresponsiveness to methacholine/histamine in patients without airflow limitations, monitoring peak expiratory flow at- and off-work, sputum eosinophil count, exhaled nitric oxide measurement, skin prick tests with occupational allergens and serum specific IgE. Treatment of OA implies avoidance of exposure, pharmacotherapy and education. OA is a heterogeneous disease. Mechanisms of its different phenotypes, their diagnosis, role of new biomarkers and treatment require further investigation.

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“…The diagnosis and management of occupational allergic diseases and asthma are often difficult. The relative role of nasal, ocular, and bronchial symptoms may be complicated, 97 and they often overlap 67 . MASK‐air® can assess days with exposure to work.…”

Section: Digital Biomarkers In Occupational Allergy and Asthmamentioning

confidence: 99%

Patient‐centered digital biomarkers for allergic respiratory diseases and asthma: The ARIA‐EAACI approach – ARIA‐EAACI Task Force Report

Bousquet

Shamji

Antó

et al. 2023

Allergy

Self Cite

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Biomarkers for the diagnosis, treatment and follow‐up of patients with rhinitis and/or asthma are urgently needed. Although some biologic biomarkers exist in specialist care for asthma, they cannot be largely used in primary care. There are no validated biomarkers in rhinitis or allergen immunotherapy (AIT) that can be used in clinical practice. The digital transformation of health and health care (including mHealth) places the patient at the center of the health system and is likely to optimize the practice of allergy. Allergic Rhinitis and its Impact on Asthma (ARIA) and EAACI (European Academy of Allergy and Clinical Immunology) developed a Task Force aimed at proposing patient‐reported outcome measures (PROMs) as digital biomarkers that can be easily used for different purposes in rhinitis and asthma. It first defined control digital biomarkers that should make a bridge between clinical practice, randomized controlled trials, observational real‐life studies and allergen challenges. Using the MASK‐air app as a model, a daily electronic combined symptom‐medication score for allergic diseases (CSMS) or for asthma (e‐DASTHMA), combined with a monthly control questionnaire, was embedded in a strategy similar to the diabetes approach for disease control. To mimic real‐life, it secondly proposed quality‐of‐life digital biomarkers including daily EQ‐5D visual analogue scales and the bi‐weekly RhinAsthma Patient Perspective (RAAP). The potential implications for the management of allergic respiratory diseases were proposed.

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Occupational asthma

Cited by 17 publications

References 36 publications

Exposures and Health Effects of Bioaerosols in Seafood Processing Workers - a Position Statement

Exposures and Health Effects of Bioaerosols in Seafood Processing Workers - a Position Statement

Progress in Occupational Asthma

Patient‐centered digital biomarkers for allergic respiratory diseases and asthma: The ARIA‐EAACI approach – ARIA‐EAACI Task Force Report

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