Occupational asthma due to mitoxantrone

Exposure of family members to antineoplastic drugs via excreta of treated cancer patients

“…To date, numerous studies have demonstrated the occurrence of adverse effects due to occupational exposure to antineoplastic drugs, including acute allergic reactions, carcinogenicity, genotoxicity, fetal abortion and congenital anomalies. 1 –13…”

“…To date, numerous studies have demonstrated the occurrence of adverse effects due to occupational exposure to antineoplastic drugs, including acute allergic reactions, carcinogenicity, genotoxicity, fetal abortion and congenital anomalies. [1][2][3][4][5][6][7][8][9][10][11][12][13] Antineoplastic drugs are classified as hazardous drugs that exhibit cytotoxicity. Various guidelines have been issued to ensure their safe use (National Institute for Occupational Safety and Health; 14 Occupational Safety and Health Administration; 15 American Society of Health System Pharmacists; 16 Oncology Nursing Society; 17 Health, & Safety Executive 18 ).…”

Occupational rhinosinusitis due to etoposide, an antineoplastic agent

“…To our knowledge, occupational hypersensitivity to etoposide among hospital staff has not been reported before. There is one report from Poland of occupational asthma due to another antineoplastic drug, mitoxantrone, confirmed by bronchial provocation and bronchoalveolar lavage (4).…”

Development of a simple compatibility inspection method using pressure in a BD PhaSeal™ system and hazardous drug vials

“…8 Healthcare workers exposed to hazardous drugs over a long period of time are at risk of health damage. 11,12 Closed system drug transfer devices (CSTD) have been shown to be useful tools for the reduction of occupational and environmental exposure to hazardous drugs. 13–17 Both NIOSH and ISOPP define a CSTD as “a drug transfer device that mechanically prohibits the transfer of environmental contaminants into the system and the escape of hazardous drug or vapor concentrations outside the system”.…”