1989
DOI: 10.1136/oem.46.11.820
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Occupational asthma due to unheated polyvinylchloride resin dust.

Abstract: Polyvinylchloride (PVC) resins are widely used in industry. Asthma due to the thermal degradation products of PVC are well documented. In this first case of occupational asthma due to unheated PVC resin dust the patient was exposed to PVC resin dust during the mixing of chemicals used for making plastic seals for bottle caps.Meatwrappers' asthma and asthma due to the thermal degradation products of polyvinylchloride (PVC) are well documented.'4 Pneumoconiosis'9 and interstitial pneumonitis'°among workers expo… Show more

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Cited by 17 publications
(15 citation statements)
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“…The second type of PVC-associated OA, of which the present case is an example, is caused by unheated PVC resin dust. While a significant decrease in PEFR was observed beginning 9 hr after bronchial challenge in a previous report (6), the FEV 1 in the present case began to decrease 10 min post-exposure, reaching a maximal decrease 1 hr after exposure. Because other laboratory tests, such as skin tests with PVC and sputum analysis, were not performed in the previous case, the pathogenic mechanism of unheated PVC dust was not determined.…”
Section: Discussioncontrasting
confidence: 68%
See 1 more Smart Citation
“…The second type of PVC-associated OA, of which the present case is an example, is caused by unheated PVC resin dust. While a significant decrease in PEFR was observed beginning 9 hr after bronchial challenge in a previous report (6), the FEV 1 in the present case began to decrease 10 min post-exposure, reaching a maximal decrease 1 hr after exposure. Because other laboratory tests, such as skin tests with PVC and sputum analysis, were not performed in the previous case, the pathogenic mechanism of unheated PVC dust was not determined.…”
Section: Discussioncontrasting
confidence: 68%
“…To date, a few cases of OA induced directly by PVC dust exposure have been reported among workers in meat processing factories and those involved in manufacture of plastic seals (3, 6, 7). The case presented here is, to our knowledge, the first case of OA confirmed by bronchoprovocation tests with both PVC and Ni, and increased airway inflammation after challenge.…”
Section: Introductionmentioning
confidence: 99%
“…Это происходит в результате миграции фта латов, при соединении их с другими химическими веществами [16].…”
Section: роль токсических веществ термической деградации поливинилхлоunclassified
“…Зарубежным исследователям впер вые удалось зарегистрировать бронхоконстрикцию после экспозиции паров ПВХ и дыма от наклеенной этикетки. Имеются данные о том, что ПВХ способен вызвать БА не в расплавленном состоянии [16]. Вы сокие концентрации фталатов у рабочих пластмас сового производства вызывали тяжелые отравления и отек легких [3,20].…”
Section: патогенные свойства фталатов и других токсических веществ сunclassified
“…Processing plant employees exposed to PVC thermal degradation products [7], unheated PVC resin dust [8] and phthalic acid esters from phthalate plasticisers [9] may suffer from occupational health effects such as workrelated asthma, bronchial disease and mixed connective tissue disease.…”
Section: Pvc Productionmentioning
confidence: 99%